Apigenin alleviates neuroinflammation in a mouse model of Parkinson's disease

GF Yarim, F Kazak, M Yarim, M Sozmen… - International Journal …, 2022 - Taylor & Francis
Purpose of the study The aim of this study is to evaluate the effect of apigenin on
inflammatory response in brain tissue in Parkinson's mouse model. Materials and methods …

Anti-inflammatory and neuroprotective effect of apigenin: studies in the GFAP-IL6 mouse model of chronic neuroinflammation

H Liang, S Sonego, E Gyengesi, A Rangel… - Free Radical Biology …, 2017 - Elsevier
Background Chronic neuroinflammation (activation of microglia and astrocytes) is a
prominent pathological process in many neurodegenerative diseases including Alzheimer's …

Protection of MPTP-induced neuroinflammation and neurodegeneration by Pycnogenol

MM Khan, D Kempuraj, R Thangavel… - Neurochemistry …, 2013 - Elsevier
Oxidative stress and inflammation play a crucial role in Parkinson's disease (PD)
pathogenesis and may represent a target for treatment. Current PD drugs provide only …

Escin attenuates behavioral impairments, oxidative stress and inflammation in a chronic MPTP/probenecid mouse model of Parkinson׳ s disease

GP Selvakumar, U Janakiraman, MM Essa… - Brain research, 2014 - Elsevier
Parkinson׳ s disease (PD) is a progressive neurodegenerative disorder that results mainly
due to the death of dopaminergic neurons in the substantia nigra (SN), and subsequently …

Eupatilin prevents behavioral deficits and dopaminergic neuron degeneration in a Parkinson's disease mouse model

Y Zhang, L Qin, J Xie, J Li, C Wang - Life sciences, 2020 - Elsevier
Aims Neuroinflammation and apoptosis play a crucial role in Parkinson's disease (PD)
pathogenesis. Eupatilin is a lipophilic flavonoid isolated from Artemisia species and exerts …

Apigenin attenuates functional and structural alterations via targeting NF-kB/Nrf2 signaling pathway in LPS-induced parkinsonism in experimental rats: Apigenin …

M Patel, S Singh - Neurotoxicity Research, 2022 - Springer
Parkinson's disease (PD) is a progressive hypokinetic movement disorder caused by
selective degeneration of dopaminergic neurons in striatum and dopamine deficiency in a …

[HTML][HTML] Arbutin effectively ameliorates the symptoms of Parkinson's disease: the role of adenosine receptors and cyclic adenosine monophosphate

J Zhao, M Kumar, J Sharma, Z Yuan - Neural regeneration …, 2021 - journals.lww.com
An antagonistic communication exists between adenosinergic and dopaminergic signaling
in the basal ganglia, which suggests that the suppression of adenosine A 2A receptors …

[HTML][HTML] Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced Parkinson's disease mouse model

W Yang, YH Chen, H Liu… - … journal of molecular …, 2015 - spandidos-publications.com
Parkinson's disease (PD) is second only to Alzheimer's disease as the most common and
debilitating age-associated neurodegenerative disorder. Currently, no therapy has been …

L-Theanine alleviates MPTP-induced Parkinson's disease by targeting Wnt/β-catenin signaling mediated by the MAPK signaling pathway

K Ratih, YR Lee, KH Chung, KJ Lee, DH Kim… - International Journal of …, 2023 - Elsevier
We evaluated the neuroprotective effect of L-theanine in Parkinson's disease and the
underlying mechanism focusing on WNT/β-catenin signaling mediated by the MAPK …

[HTML][HTML] Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson's disease

HY Yu, T Sun, Z Wang, H Li, D Xu, J An… - Neural Regeneration …, 2023 - journals.lww.com
Use of glucagon-like peptide-1 receptor agonist or dipeptidyl peptidase 4 inhibitor has been
shown to lower the incidence of Parkinson's disease in patients with diabetes mellitus …