Importance of the field: Dendritic cells (DC) are powerful antigen-presenting cells that induce
and maintain primary cytotoxic T lymphocyte (CTL) responses directed against tumor …

Dendritic cell-based immunotherapy is a promising strategy against cancer that appears to
be feasible, safe and to induce potent tumor-specific immune responses. The use of …

Importance of the field: Dendritic cells (DC) are a clear choice for use in cancer
immunotherapy, and much research has focused on generating DC for clinical use …

It has been more than 100 years since Dr. William B. Coley reported the regression of
tumors in some patients who had been injected with bacterial extracts [1]. Since this early …

The discovery of tumor-associated antigens, which are either selectively or preferentially
expressed by tumors, together with an improved insight in dendritic cell biology illustrating …

Although T-cell-defined tumor antigens have recently been identified in several tumors,
human neoplastic cells are considered to be poorly immunogenic. The development of …

Dendritic cells (DC) are potent antigen presenting cells that are essential for the initiation of
primary immune responses. They richly express MHC, costimulatory and adhesion …

Dendritic cells (DCs) are the professional antigen-presenting cells of the immune system,
with the potential to either stimulate or inhibit immune responses. Exploiting the immune …

ABSTRACT B and T lymphocytes are the effectors of specific immunity. However, their
function is critically dependent on dendritic cells (DC). DC are professional antigen …

Despite initial enthusiasm, dendritic cell (DC)‐based anti‐cancer vaccines have yet to live
up to their promise as one of the best hopes for generating effective anti‐tumor immunity …