Assessment of 2-year neurodevelopmental outcomes in extremely preterm infants receiving opioids and benzodiazepines

M Puia-Dumitrescu, BA Comstock, S Li… - JAMA Network …, 2021 - jamanetwork.com
Importance Extremely preterm (EP) infants frequently receive opioids and/or
benzodiazepines, but these drugs' association with neurodevelopmental outcomes is poorly …

Morphine exposure and neurodevelopmental outcome in infants born extremely preterm

M Luzzati, C Coviello, HS De Veye… - … Medicine & Child …, 2023 - Wiley Online Library
Aim To investigate the association between morphine exposure in the neonatal period and
neurodevelopment at 2 and 5 years of age while controlling for potential confounders …

Evaluation of the relationship between opioid exposure in extremely low birth weight infants in the neonatal intensive care unit and neurodevelopmental outcome at 2 …

M Kocek, R Wilcox, C Crank, K Patra - Early human development, 2016 - Elsevier
Background Extremely low birth weight (ELBW) infants are exposed to many painful
procedures while in the neonatal intensive care unit (NICU), such as catheter insertion and …

Association of fentanyl with neurodevelopmental outcomes in very-low-birth-weight infants

EM Lammers, PN Johnson, KD Ernst… - Annals of …, 2014 - journals.sagepub.com
Background: Opioids are commonly used in the neonatal intensive care unit (NICU).
Negative neurodevelopmental effects in the short-term setting have been associated with …

Smaller cerebellar growth and poorer neurodevelopmental outcomes in very preterm infants exposed to neonatal morphine

JG Zwicker, SP Miller, RE Grunau, V Chau… - The Journal of …, 2016 - Elsevier
Objective To examine the relationship between morphine exposure and growth of the
cerebellum and cerebrum in very preterm neonates from early in life to term-equivalent age …

Dexamethasone, prednisolone, and methylprednisolone use and 2-year neurodevelopmental outcomes in extremely preterm infants

M Puia-Dumitrescu, TR Wood, BA Comstock… - JAMA network …, 2022 - jamanetwork.com
Importance Practice variability exists in the use of corticosteroids to treat or prevent
bronchopulmonary dysplasia in extremely preterm infants, but there is limited information on …

Outcomes of extremely preterm infants with birth weight less than 400 g

JE Brumbaugh, NI Hansen, EF Bell, A Sridhar… - JAMA …, 2019 - jamanetwork.com
Importance Birth weight (BW) is an important predictor of mortality and morbidity. At
extremely early gestational ages (GAs), BW may influence decisions regarding initiation of …

Neonatal morphine exposure in very preterm infants—cerebral development and outcomes

R Steinhorn, C McPherson, PJ Anderson, J Neil… - The Journal of …, 2015 - Elsevier
Objective To investigate the association of morphine exposure in very preterm infants with
cerebral volumes and neurodevelopmental outcome from birth through middle childhood …

Prenatal opioid exposure: neurodevelopmental consequences and future research priorities

E Conradt, T Flannery, JL Aschner, RD Annett… - …, 2019 - publications.aap.org
Neonatal opioid withdrawal syndrome (NOWS) has risen in prevalence from 1.2 per 1000
births in 2000 to 5.8 per 1000 births in 2012. Symptoms in neonates may include high …

Deaths in a modern cohort of extremely preterm infants from the preterm erythropoietin neuroprotection trial

SE Juul, TR Wood, BA Comstock, K Perez… - JAMA Network …, 2022 - jamanetwork.com
Importance Understanding why and how extremely preterm infants die is important for
practitioners caring for these infants. Objective To examine risk factors, causes, timing, and …