Angiogenesis is the process of generating new blood vessels from existing ones. Vascular
endothelial growth factors (VEGFs) and their receptors (VEGFRs) are the main proteins and …

Angiogenesis, the formation of new blood vessels from pre–-existing ones, is central for both
normal development and homeostasis as well as in certain pathological conditions. The …

VEGFR-3 is essential for vascular development and maintenance of lymphatic vessel's
integrity. Little is known about its cooperative effect with other receptors of the same family …

Background Vascular endothelial growth factors (VEGFs) are potential therapeutic agents
for treatment of ischemic diseases. Their angiogenic effects are mainly mediated through …

Vascular endothelial growth factor (VEGF) signaling is tightly regulated by specific VEGF
receptors (VEGF-R). Recently, we identified heterodimerisation between VEGFR-1 and …

Vascular endothelial growth factors (VEGFs) and their receptors play key roles in
angiogenesis and lymphangiogenesis. VEGF activates VEGF receptor-1 (VEGFR-1) and …

The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central
regulatory role in physiological and pathological angiogenesis. During embryogenesis, the …

Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …

VEGFR-1 is devoid of ligand-dependent tyrosine autophosphorylation and its activation is
not associated with proliferation of endothelial cells. The molecular mechanism responsible …

Vascular endothelial growth factor (VEGF)-A165b is a COOH-terminal splice variant of VEGF-
A that has been implicated in negative regulation of angiogenesis. We compared the …