Few neoplastic diseases have undergone a transformation in a relatively short period like
chronic myeloid leukemia (CML) has in the last few years. In 1960, CML was the first cancer …

Chronic Myelogenous Leukemia Clinical Practice Guidelines in Oncology NCCN Categories
of Evidence and Consensus Category 1: The recommendation is based on high-level …

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a
characteristic clinical course in which a chronic phase of variable duration precedes an …

Purpose. Chronic myeloid leukemia (CML), a hematopoietic stem cell cancer representing
15–20% of adult leukemias, is discussed. Epidemiology, staging biology, and monitoring …

Purpose of review In this review, we emphasize up-to-date practical cytogenetic and
molecular aspects of chronic myeloid leukemia (CML) and summarize current knowledge on …

Chronic myeloid leukemia (CML) is a pluripotent hematopoietic stem cell disorder leading to
myeloproliferation and its attendant consequences. In the United States, it is estimated that …

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic
stem cells. At the molecular level, the disorder results from t (9; 22)(q34; q11) reciprocal …

Chronic myeloid leukemia (CML) is characterized by the Philadelphia translocation that
fuses BCR sequences from chromosome 22 upstream of the ABL gene on chromosome 9 …

Chronic myeloid leukemia (CML) has been the first human malignancy to be associated,
more than 50 years ago, with a consistent chromosomal abnormality—the t (9; 22)(q34; q11) …

Patients with splenomegaly and abnormally high leukocyte counts were first recognized in
France, Germany, and Scotland in the 1840s. The only well-documented therapy in the 19th …