Low isobutanol tolerance of Saccharomyces cerevisiae limits its application in isobutanol
fermentation. Here, we used global transcription machinery engineering to screen mutants …

Improving yeast tolerance toward isobutanol is a critical issue enabling high-titer industrial
production. Here, we used EMS mutagenesis to screen Saccharomyces cerevisiae with …

Background: Isobutanol is an ideal second-generation biofuels due to its lower
hygroscopicity, higher energy density and higher-octane value. However, isobutanol is toxic …

To investigate effects of different pyruvate decarboxylases on isobutanol titers in
Saccharomyces cerevisiae, single-gene deletion of the three PDCs genes encoding …

Microbial cell factory, which converts biomass feedstock to value-added compounds such as
fuels, chemicals, materials and pharmaceuticals, has been proposed as a sustainable and …

As one of the microorganism commonly used in industrial production, Saccharomyces
cerevisiae is of low pH resistance and strong stress resistance. The use of microorganisms …

As a new biofuel, isobutanol has received more attentions in recent years. Because of its
high tolerance to higher alcohols, Saccharomyces cerevisiae has potential advantages as a …

Background n-Butanol and isobutanol produced from biomass-derived sugars are promising
renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for …

Saccharomyces cerevisiae naturally produces small amounts of isobutanol and 3-methyl-1-
butanol via Ehrlich pathway from the catabolism of valine and leucine, respectively. In this …

Ethanol tolerance involves complex interactions of several genes in the Saccharomyces
cerevisiae genome that encodes proteins that are the subunits of the SAGA (Spt-Ada-Gcn5 …