Multiplexed profiling of extracellular vesicles for biomarker development

C Jiang, Y Fu, G Liu, B Shu, J Davis, GK Tofaris - Nano-micro letters, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

Multiplexed profiling of single extracellular vesicles

K Lee, K Fraser, B Ghaddar, K Yang, E Kim, L Balaj… - ACS …, 2018 - ACS Publications
Extracellular vesicles (EV) are a family of cell-originating, membrane-enveloped
nanoparticles with diverse biological function, diagnostic potential, and therapeutic …

Extracellular vesicle quantification and characterization: common methods and emerging approaches

TA Hartjes, S Mytnyk, GW Jenster, V van Steijn… - Bioengineering, 2019 - mdpi.com
Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information
about cells by which they are secreted. Growing interest in the role of EVs in intercellular …

Analysis and biomedical applications of functional cargo in extracellular vesicles

F Qian, Z Huang, H Zhong, Q Lei, Y Ai, Z Xie, T Zhang… - ACS …, 2022 - ACS Publications
Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …

From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization

M Chen, S Lin, C Zhou, D Cui, H Haick… - Advanced Healthcare …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …

Multiplexed profiling of biomarkers in extracellular vesicles for cancer diagnosis and therapy monitoring

S Zhou, Y Yang, Y Wu, S Liu - Analytica chimica acta, 2021 - Elsevier
Extracellular vesicles (EVs) are nanoscale vesicles secreted by normal and pathological
cells. The types and levels of surface proteins and internal nucleic acids in EVs are closely …

Advances in extracellular vesicle nanotechnology for precision theranostics

Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

Opportunities and pitfalls of fluorescent labeling methodologies for extracellular vesicle profiling on high-resolution single-particle platforms

D Fortunato, D Mladenović, M Criscuoli, F Loria… - International Journal of …, 2021 - mdpi.com
The relevance of extracellular vesicles (EVs) has grown exponentially, together with
innovative basic research branches that feed medical and bioengineering applications …