New Findings What is the central question of this study? Between 60 and 80% of multiple
sclerosis (MS) patients experience transient worsening of symptoms with increased body …

Multiple sclerosis (MS) is an autoimmune neurodegenerative disease characterized by
demyelination of the central nervous system (CNS). The exact cause of MS is still unknown; …

Heat sensitivity is a well-recognised feature in multiple sclerosis (MS). However, little is
known about how heat affects physical performance in persons with MS. The objective of the …

We investigated whether and how multiple sclerosis (MS) alters thresholds for perceiving
increases and decreases in local skin temperature, as well as the sensitivity to progressively …

Impairments in sudomotor function during passive heat stress have been reported in
multiple sclerosis (MS), a demyelinating disease of the CNS that disrupts autonomic …

The negative effects of thermal stress on Multiple Sclerosis (MS)'symptoms have long been
known. However, the underlying mechanisms of MS heat and cold intolerance remain …

In 1890, Uhthoff studied multiple sclerosis (MS) patients who developed amblyopia following
exercise, a phenomenon later discovered to be secondary to elevated body temperature …

Background: Heat sensitivity (HS) is reported by 58% of all persons with multiple sclerosis
(MS), causing symptom exacerbation possibly limiting exercise participation. Objective: The …

Multiple sclerosis (MS) is a progressive neurological disorder that disrupts axonal myelin in
the central nervous system. Demyelination produces alterations in saltatory conduction …

Background Thermo sensitivity (TS), characterized by worsening of neurological symptoms
due to increased body temperature, is common in individuals with multiple sclerosis (MS) …