Phage diversity for research and application

C Rohde, J Wittmann - Antibiotics, 2020 - mdpi.com
Bacteriophages (in short, phages) are viruses that specifically recognize and infect bacteria;
they are the most abundant forms of life in the biosphere outnumbering bacteria by an …

Grand challenges in phage biology

S Ryu - Frontiers in Microbiology, 2021 - frontiersin.org
Over one century has passed since William Twort first discovered phages in 1915 and Felix
d'Herelle recognized their potential as antibacterial agents in 1917 (Clokie et al., 2011) …

Back to the future: bacteriophages as promising therapeutic tools

P Domingo‐Calap, P Georgel, S Bahram - Hla, 2016 - Wiley Online Library
Bacteriophages (phages), natural predators of bacteria, are becoming increasingly attractive
in medical and pharmaceutical applications. After their discovery almost a century ago, they …

Phage life cycles behind bacterial biodiversity

T Olszak, A Latka, B Roszniowski… - Current medicinal …, 2017 - ingentaconnect.com
Bacteriophages (phages or bacterial viruses) are the most abundant biological entities in
our planet; their influence reaches far beyond the microorganisms they parasitize. Phages …

Isolation, screening and characterization of phage

BM Zaki, AA Mohamed, A Dawoud, K Essam… - Progress in Molecular …, 2023 - Elsevier
Bacterial resistance threatens public health due to a lack of novel antibacterial classes since
the 21 st century. Bacteriophages, the most ubiquitous microorganism on Earth and natural …

Phages & antibiotic resistance: are the most abundant entities on earth ready for a comeback?

C Hill, S Mills, RP Ross - Future microbiology, 2018 - Taylor & Francis
Bacteriophages, which lost out to antibiotic therapy in the past, may be poised to make a
comeback. Once discarded because of their narrow activity spectrum, it can now be viewed …

Myriad applications of bacteriophages beyond phage therapy

JC García-Cruz, D Huelgas-Méndez… - PeerJ, 2023 - peerj.com
Bacteriophages are the most abundant biological entity on the planet, having pivotal roles in
bacterial ecology, animal and plant health, and in the biogeochemical cycles. Although, in …

Bacteriophages: emerging applications in medicine, food, and biotechnology

HA Sohail, A Coffey, K Debrowska, IM Meyer… - Phage, 2020 - liebertpub.com
The repertoire of bacteriophage applications has expanded considerably in the past
decade. The potential of bacteriophages to be exploited as antimicrobial agents has …

Exploring the potential of bacteriophages on earth and beyond

A Mohanty, B Shaw, N Pradeep, NK Singh… - Journal of the Indian …, 2023 - Springer
Bacteriophages are ubiquitous, from natural environments to human-made shelters. Their
prevalence is governed mainly by their host bacteria, leading to their coevolution with …

Use of phages as antimicrobial agents

HW Bae, ES Kim, YH Cho - Molecular Medical Microbiology, 2024 - Elsevier
Historically bacteriophages (phages) have been used to treat bacterial infections and have
some advantages over antibiotics, especially in this era of antimicrobial resistance. The …