Impact of gulf war toxic exposures after mild traumatic brain injury

S Ferguson, R McCartan, M Browning… - Acta Neuropathologica …, 2022 - Springer
Chemical and pharmaceutical exposures have been associated with the development of
Gulf War Illness (GWI), but how these factors interact with the pathophysiology of traumatic …

A chronic longitudinal characterization of neurobehavioral and neuropathological cognitive impairment in a mouse model of Gulf War agent exposure

Z Zakirova, G Crynen, S Hassan, L Abdullah… - Frontiers in integrative …, 2016 - frontiersin.org
Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system
component that includes memory impairment as well as neurological and musculoskeletal …

Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness

Z Zakirova, M Tweed, G Crynen, J Reed, L Abdullah… - PloS one, 2015 - journals.plos.org
Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system
component such as memory deficits, neurological, and musculoskeletal problems. There are …

Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness

B Hattiangady, V Mishra, M Kodali, B Shuai… - Frontiers in behavioral …, 2014 - frontiersin.org
Memory and mood deficits are the enduring brain-related symptoms in Gulf War illness
(GWI). Both animal model and epidemiological investigations have indicated that these …

Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease

I Carreras, N Aytan, T Mellott, JK Choi, M Lehar… - Brain research, 2018 - Elsevier
Abstract Gulf War Illness (GWI) is a chronic disease that affects the 1991 Gulf War (GW)
veterans for which treatment is lacking. It has been hypothesized that drugs used to protect …

Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness

L Abdullah, JE Evans, U Joshi, G Crynen, J Reed… - Toxicology, 2016 - Elsevier
Abstract Gulf War Illness (GWI) affects 25% of veterans from the 1990–1991 Gulf War (GW)
and is accompanied by damage to the brain regions involved in memory processing. After …

The multiple hit hypothesis for gulf war illness: self-reported chemical/biological weapons exposure and mild traumatic brain injury

P Janulewicz, M Krengel, E Quinn, T Heeren… - Brain sciences, 2018 - mdpi.com
The Gulf War Illness Consortium (GWIC) was designed to identify objective biomarkers of
Gulf War Illness (GWI) in 1991 Gulf War veterans. The symptoms of GWI include fatigue …

Altered hippocampal function and cytokine levels in a rat model of Gulf War illness

NM Gargas, VT Ethridge, MK Miklasevich, JG Rohan - Life Sciences, 2021 - Elsevier
Abstract Aims Gulf War illness (GWI) is a disorder affecting military personnel deployed in
the Gulf War (GW) from 1990 to 1991. Here, we will use a rat model of GWI to evaluate …

Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents

L Abdullah, G Crynen, J Reed, A Bishop… - Neuromolecular …, 2011 - Springer
Abstract Gulf War Illness (GWI) is a chronic multisymptom condition with a central nervous
system (CNS) component, for which there is no treatment available. It is now believed that …

Exposure to an organophosphate pesticide, individually or in combination with other G ulf W ar agents, impairs synaptic integrity and neuronal differentiation, and is …

JO Ojo, L Abdullah, J Evans, JM Reed… - …, 2014 - Wiley Online Library
Gulf War illness (GWI) is a currently untreatable multi‐symptom disorder experienced by
1990–1991 Persian Gulf War (GW) veterans. The characteristic hallmarks of GWI include …