Schizotypal disorder is characterized by odd behavior and attenuated forms of
schizophrenic features without the manifestation of overt and sustained psychoses. Past …

BackgroundAlterations of cortical thickness have been shown in imaging studies of
schizophrenia but it is unclear to what extent they are related to disease phenotype …

Schizophrenia is an etiologically and clinically heterogeneous disorder. Although
neuroimaging studies have revealed brain alterations in schizophrenia, most studies have …

Context Whether cortical thickness changes in schizophrenia over time are more
pronounced relative to the changes that can be attributed to normal aging has not been …

Schizophrenia is a severe psychiatric illness with widespread impairments of cognitive
functioning; however, a certain percentage of subjects are known to perform in the normal …

A considerable body of evidence from structural brain imaging studies suggests that patients
with schizophrenia have significant alterations of gray matter density. Additionally, recently …

Background Schizophrenia is characterized by small reductions in cortical gray matter
volume, particularly in the temporal and prefrontal cortices. The question of whether cortical …

OBJECTIVE: Cortical thickness reductions in prefrontal and temporal cortices have been
repeatedly observed in patients with schizophrenia. However, it remains unclear whether …

Cortical abnormalities are considered a neurobiological characteristic of schizophrenia.
However, the pattern of such deficits as they progress over the illness remains poorly …

Morphological abnormalities of the cerebral cortex have been reported in a number of MRI-
studies in schizophrenia. Uncertainty remains regarding cause, mechanism and progression …