Background Despite treatment according to the current management recommendations, a
significant proportion of patients with rheumatoid arthritis (RA) remain symptomatic. These …

Objectives Patients with difficult-to-treat rheumatoid arthritis (RA) remain symptomatic
despite treatment according to current European League Against Rheumatism (EULAR) …

Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

Increased effectiveness of pharmacological treatments in early RA has led many to believe
that difficult-to-treat, established RA is a condition of the past. However, there are still plenty …

The European Alliance of Associations for Rheumatology recently defined difficult to treat
(D2T) rheumatoid arthritis (RA) and provided points to consider in its management. This …

Objectives To summarise, by a systematic literature review (SLR), the evidence regarding
pharmacological and non-pharmacological therapeutic strategies in difficult-to-treat …

Over the past several decades, the treatment of rheumatoid arthritis (RA) has advanced
significantly, and clinical, structural, and functional remission are achievable therapeutic …

Objectives Treatment of difficult-to-treat (D2T) RA patients is generally based on trial-and-
error and can be challenging due to a myriad of contributing factors. We aimed to identify …

Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear
and consensual international recommendations on RA treatment are not available. In this …

In this article, the 2010 European League against Rheumatism (EULAR) recommendations
for the management of rheumatoid arthritis (RA) with synthetic and biological disease …