Objectives To determine, 6 years after the adoption of intermittent preventive treatment of
pregnant women with sulfadoxine/pyrimethamine (IPTp-SP) in Cameroon,(i) the …

Background Sulfadoxine–pyrimethamine (SP) is recommended for prophylactic treatment of
malaria in pregnancy while artemisinin combination therapy is the recommended first-line …

There are few published reports of mutations in dihydropteroate synthetase (dhps) and
dihydrofolate reductase (dhfr) genes in P. falciparum populations in Nigeria, but one …

Background The emergence of drug resistance in Plasmodium falciparum has been a major
contributor to the global burden of malaria. Drug resistance complicates treatment, and it is …

Background The malaria situation has been worsening in Angola, partly due to armed
conflict until the recent past and drug-resistant Plasmodium falciparum. Malaria transmission …

Abstract Background Malaria in Yemen is mainly caused by Plasmodium falciparum and
25% of the population is at high risk. Sulfadoxine–pyrimethamine (SP) had been used as …

Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine–
pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is …

Sulfadoxine-pyrimethamine (SP) resistance in Plasmodium falciparum is encoded by a
number of mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthetase …

The emergence and spread of Plasmodium falciparum parasite resistant to sulfadoxine and
pyrimethamine (SP) poses a serious public health problem. Resistance is caused by point …

Faced with intense levels of chloroquine (CQ) resistance in Plasmodium falciparum malaria,
Rwanda replaced CQ with amodiaquine (AQ)+ sulfadoxine-pyrimethamine (SP) in 2001 …