[HTML][HTML] Overexpression of GDNF in the uninjured DRG exerts analgesic effects on neuropathic pain following segmental spinal nerve ligation in mice
K Takasu, A Sakai, H Hanawa, T Shimada, H Suzuki - The Journal of Pain, 2011 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF), a survival-promoting factor for a subset of
nociceptive small-diameter neurons, has been shown to exert analgesic effects on …
nociceptive small-diameter neurons, has been shown to exert analgesic effects on …
Glial cell line-derived neurotrophic factor contributes to delayed inflammatory hyperalgesia in adjuvant rat pain model
Neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor, are
members of the structurally related neurotrophin family that play important roles in pain …
members of the structurally related neurotrophin family that play important roles in pain …
Decreased expression of glial cell line‐derived neurotrophic factor signaling in rat models of neuropathic pain
M Nagano, A Sakai, N Takahashi… - British Journal of …, 2003 - Wiley Online Library
In an attempt to clarify whether glial cell line‐derived neurotrophic factor (GDNF), a survival
factor for subpopulations of primary afferent neurons, is involved in the states of neuropathic …
factor for subpopulations of primary afferent neurons, is involved in the states of neuropathic …
A potential anti-allodynic mechanism of GDNF following L5 spinal nerve ligation; Mitigation of NPY up-regulation in the touch sense pathway
T Fukuoka, K Noguchi - Neuroscience, 2015 - Elsevier
Intrathecal delivery of glial cell line-derived neurotrophic factor (GDNF) reverses mechanical
allodynia after 5th lumbar (L5) spinal nerve ligation (SNL). However, the molecular …
allodynia after 5th lumbar (L5) spinal nerve ligation (SNL). However, the molecular …
Involvement of neural cell adhesion molecule signaling in glial cell line-derived neurotrophic factor-induced analgesia in a rat model of neuropathic pain
A Sakai, M Asada, N Seno, H Suzuki - PAIN®, 2008 - Elsevier
Since neuropathic pain is resistant to conventional analgesics such as opiates and non-
steroidal anti-inflammatory drugs, the development of new types of drugs for its treatment …
steroidal anti-inflammatory drugs, the development of new types of drugs for its treatment …
Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental …
R Wang, W Guo, MH Ossipov, TW Vanderah, F Porreca… - Neuroscience, 2003 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) is necessary for the development of
sensory neurons, and appears to be critical for the survival of dorsal root ganglion (DRG) …
sensory neurons, and appears to be critical for the survival of dorsal root ganglion (DRG) …
Effects of glial cell line-derived neurotrophic factor intrathecal injection on spinal dorsal horn glial fibrillary acidic protein expression in a rat model of neuropathic pain
J Guo, D Jia, B Jin, F Xu, X Yuan… - International Journal of …, 2012 - Taylor & Francis
Glial fibrillary acidic protein (GFAP) is a specific astrocytic marker in the central nervous
system. Few studies on the effects of glial cell line-derived neurotrophic factor (GDNF) …
system. Few studies on the effects of glial cell line-derived neurotrophic factor (GDNF) …
Expression changes of glial cell line-derived neurotrophic factor in a rat model of neuropathic pain
N Takahashi, M Nagano, H Suzuki… - Journal of Medical and …, 2003 - jstage.jst.go.jp
To reveal roles of neurotrophic factors in plastic changes of the primary afferent neurons
following nerve injury, we investigated expression of glial cell line-derived neurotrophic …
following nerve injury, we investigated expression of glial cell line-derived neurotrophic …
Normalizing GDNF expression in the spinal cord alleviates cutaneous hyperalgesia but not ongoing pain in a rat model of bone cancer pain
Z Ding, W Xu, J Zhang, W Zou, Q Guo… - … Journal of Cancer, 2017 - Wiley Online Library
Bone cancer pain (BCP) is the most common complication in patients with bone cancer.
Glial cell line‐derived neurotrophic factor (GDNF) is believed to be involved in chronic pain …
Glial cell line‐derived neurotrophic factor (GDNF) is believed to be involved in chronic pain …
Intrathecal injection of GDNF and BDNF induces immediate early gene expression in rat spinal dorsal horn
JLM Jongen, ED Haasdijk, H Sabel-Goedknegt… - Experimental …, 2005 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor
(BDNF) are potent trophic factors for dorsal root ganglion cells. In addition, these factors are …
(BDNF) are potent trophic factors for dorsal root ganglion cells. In addition, these factors are …