Baseline tumour measurements predict survival in advanced non-small cell lung cancer

DE Gerber, SE Dahlberg, AB Sandler, DH Ahn… - British journal of …, 2013 - nature.com
Background: The association between tumour measurements and survival has been studied
extensively in early-stage and locally advanced non-small cell lung cancer (NSCLC). We …

[HTML][HTML] Korean real-world data on patients with unresectable stage III NSCLC treated with durvalumab after chemoradiotherapy: PACIFIC-KR

CK Park, HJ Oh, YC Kim, YH Kim, SJ Ahn… - Journal of Thoracic …, 2023 - Elsevier
Introduction This study aimed to investigate real-world evidence for efficacy and safety of
durvalumab consolidation (DC) after chemoradiotherapy (CRT) in patients with unresectable …

[HTML][HTML] Low peripheral blood derived neutrophil-to-lymphocyte ratio (dNLR) is associated with increased tumor T-cell infiltration and favorable outcomes to first-line …

JV Alessi, B Ricciuti, SL Alden, AA Bertram… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background An elevated peripheral blood derived neutrophil-to-lymphocyte ratio (dNLR) is
a negative prognostic marker for patients with non-small cell lung cancer (NSCLC) receiving …

Prediction of overall survival or progression free survival by disease control rate at week 8 is independent of ethnicity: Western versus Chinese patients with first‐line …

L Claret, M Gupta, K Han, A Joshi… - The Journal of …, 2014 - Wiley Online Library
Categorizations of best response observed at week 8 (between week 3 and 14) of first‐line
treatment in two studies of bevacizumab plus chemotherapy in Western (878 patients) and …

Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab-treated patients with advanced non-small-cell lung cancer

SJ Bagley, S Kothari, C Aggarwal, JM Bauml, EW Alley… - Lung cancer, 2017 - Elsevier
Objectives Efficient use of nivolumab in non-small-cell lung cancer (NSCLC) has been
limited by the lack of a definitive predictive biomarker. In patients with metastatic melanoma …

Abstract CT074: Tumor mutational burden (TMB) as a biomarker of survival in metastatic non-small cell lung cancer (mNSCLC): Blood and tissue TMB analysis from …

S Peters, BC Cho, N Reinmuth, KH Lee, A Luft, MJ Ahn… - Cancer Research, 2019 - AACR
Background High TMB is predictive of PFS benefit with anti-PD-(L) 1±anti-CTLA-4 therapy in
mNSCLC. Preliminary results from MYSTIC (NCT02453282), an open-label, Phase III trial of …

Durvalumab after chemoradiation for unresectable stage III non-small cell lung cancer: inferior outcomes and lack of health equity in hispanic patients treated with …

LE Raez, O Arrieta, DF Chamorro… - Frontiers in …, 2022 - frontiersin.org
Objectives To compare the rate disparity between outcomes (overall survival (OS),
progression-free survival (PFS), and safety) of concurrent chemoradiation (cCRT) followed …

Machine-learning and stochastic tumor growth models for predicting outcomes in patients with advanced non–Small-Cell lung cancer

KW Siah, S Khozin, CH Wong, AW Lo - JCO clinical cancer …, 2019 - ascopubs.org
PURPOSE The prediction of clinical outcomes for patients with cancer is central to precision
medicine and the design of clinical trials. We developed and validated machine-learning …

International Cost-Effectiveness Analysis of Durvalumab in Stage III Non–Small Cell Lung Cancer

SA Kareff, S Han, B Haaland, CJ Jani, R Kohli… - JAMA Network …, 2024 - jamanetwork.com
Importance Standard of care for unresectable locally advanced non–small cell lung cancer
(NSCLC) involves definitive chemoradiotherapy followed by maintenance therapy with …

Real-world incidence of pneumonitis in patients receiving durvalumab

JN LeClair, MY Merl, M Cohenuram, D Luon - Clinical Lung Cancer, 2022 - Elsevier
Abstract Introduction/Background Durvalumab is a programmed cell death ligand 1 (PD-L1)
inhibitor indicated for stage III, unresectable non-small cell lung cancer (NSCLC) …