Carrier strategies boost the application of CRISPR/Cas system in gene therapy

Z Xu, Q Wang, H Zhong, Y Jiang, X Shi, B Yuan… - …, 2022 - Wiley Online Library
Emerging clustered regularly interspaced short palindromic repeat/associated protein
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …

Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook

T Wan, D Niu, C Wu, FJ Xu, G Church, Y Ping - Materials Today, 2019 - Elsevier
Clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein
(CRISPR/Cas) system is an adaptable immune mechanism used by many bacteria to protect …

Synthetic multi-layer nanoparticles for CRISPR-Cas9 genome editing

H Tang, X Zhao, X Jiang - Advanced drug delivery reviews, 2021 - Elsevier
The clustered regularly interspaced short palindromic repeat (CRISPR) has great potential
to revolutionize biomedical research and disease therapy. The specific and efficient genome …

[HTML][HTML] Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing

S Zhang, J Shen, D Li, Y Cheng - Theranostics, 2021 - ncbi.nlm.nih.gov
CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities

L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …

[HTML][HTML] CRISPR/Cas9 delivery system engineering for genome editing in therapeutic applications

H Cheng, F Zhang, Y Ding - Pharmaceutics, 2021 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform …

Delivery of CRISPR/Cas9 by novel strategies for gene therapy

L Wang, W Zheng, S Liu, B Li, X Jiang - ChemBioChem, 2019 - Wiley Online Library
Precise editing of the genome of a living body is a goal pursued by scientists in many fields.
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas …

[HTML][HTML] CRISPR/Cas9 systems: delivery technologies and biomedical applications

Y Du, Y Liu, J Hu, X Peng, Z Liu - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
The emergence of the clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR-associated protein 9 (Cas9) genome-editing system has brought about a …

Development of delivery strategies for CRISPR‐Cas9 genome editing

Q Liu, J Yang, Y Xing, Y Zhao, Y Liu - BMEMat, 2023 - Wiley Online Library
The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR‐
related protein 9 (Cas9) genome editing system has attracted much attention due to its …

[HTML][HTML] Pre-clinical non-viral vectors exploited for in vivo CRISPR/Cas9 gene editing: An overview

N Rouatbi, T McGlynn, KT Al-Jamal - Biomaterials Science, 2022 - pubs.rsc.org
Clustered regulatory interspaced short palindromic repeats or CRISPR/Cas9 has emerged
as a potent and versatile tool for efficient genome editing. This technology has been …