Multidrug efflux pumps are a significant obstacle preventing the control of infections caused
by pathogenic bacteria. Genes encoding these transporters have been found in all bacterial …

The antimicrobial resistance (AMR) crisis represents one of the greatest challenges to
modern medicine this century and threatens a return to the pre-antimicrobial era. It is evident …

Objectives Drug efflux pumps are one of the key machineries in bacterial drug resistance.
Although quite a few of these transport systems have been functionally characterized in …

Several infections, such as pneumonia, urinary tract infections (UTIs), as well as
bloodstream, skin, and soft tissue infections, are caused by Acinetobacter baumannii, a …

Multidrug efflux pumps provide clinically significant levels of drug resistance in a number of
Gram-negative hospital-acquired pathogens. These pathogens frequently carry dozens of …

Multidrug efflux systems are a major cause of resistance to antimicrobials in bacteria,
including those pathogenic to humans, animals, and plants. These proteins are ubiquitous in …

Infections associated with Acinetobacter baumannii represent a major threat to public health
around the globe. This pathogen possesses the most sophisticated mechanisms of …

Objectives: Drug efflux pumps are one of the key machineries in bacterial drug resistance.
Although quite a few of these transport systems have been functionally characterized in …

Antibiotics are vital to modern medicine. However, bacterial resistance constitutes a growing
threat to effective antimicrobial therapy worldwide. Indeed, antimicrobial resistance …

Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …