Glaucoma treatment is usually initiated with topical medication that lowers the intraocular
pressure (IOP) by reducing the aqueous production, enhancing the aqueous outflow, or …

Purpose To evaluate the effects of baseline trabecular meshwork (TM) and Schlemm's canal
(SC) microstructures on intraocular pressure (IOP) reduction amount in treatment-naïve …

Glaucoma is often characterized by decreased pressure-sensitive aqueous outflow through
the trabecular meshwork. This defect in pressure-sensitive aqueous outflow is evident from …

Intraocular pressure (IOP) is the critical risk factor for glaucoma, a neurodegenerative
disease and frequent cause of blindness worldwide. As of today, all effective strategies to …

PURPOSE: To determine the effect of latanoprost free acid and prostaglandin E1 (PGE1) on
outflow facility in cultured human anterior segments. Clinical studies find prostaglandin …

Primary open-angle glaucoma (POAG) is a leading cause of irreversible and preventable
blindness and ocular hypertension is the strongest known risk factor. With current classes of …

Purpose: Aqueous humor filtration in the trabecular meshwork is believed to be non-uniform
or “segmental” such that only a fraction of trabecular meshwork is filtration-active at any …

Purpose.: To investigate morphologic changes of the corneoscleral limbus in glaucoma
patients using laser scanning confocal microscopy (LSCM) and impression cytology (IC) …

purpose. To assess the expression pattern of prostanoid receptor–encoding genes in
trabecular meshwork (TM) of human donor eyes. methods. Disposed human donor eyes (n …

Primary open-angle glaucoma (POAG) is an age-related disease and a multifaceted optic
neuropathy characterized by the loss of optic nerve axons and retinal ganglion cells …