MPTP-induced behavioural and biochemical deficits: a parametric analysis
A Fredriksson, T Archer - … of neural transmission-Parkinson's disease and …, 1994 - Springer
Two experiments were performed to study the parametric effects of long-term administration
of the neurotoxin, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP), as a functional …
of the neurotoxin, 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP), as a functional …
[引用][C] The MPTP-treated mouse as a model of parkinsonism: how good is it?
RE Heikkila, PK Sonsalla - Neurochemistry international, 1992 - Elsevier
Parkinsonism is a common neurological disorder, the causes of which are presently
unknown. There has been increasing speculation in the past several years about the …
unknown. There has been increasing speculation in the past several years about the …
Therapeutic effects of rapamycin on MPTP-induced Parkinsonism in mice
K Liu, N Shi, Y Sun, T Zhang, X Sun - Neurochemical research, 2013 - Springer
In neurodegenerative disorders such as Parkinson's disease (PD), autophagy is implicated
in the process of dopaminergic neuron cell death. The α-synuclein protein is a major …
in the process of dopaminergic neuron cell death. The α-synuclein protein is a major …
[HTML][HTML] Historical perspective: models of Parkinson's disease
SJ Chia, EK Tan, YX Chao - International journal of molecular sciences, 2020 - mdpi.com
Parkinson's disease (PD) is the most common movement disorder with motor and nonmotor
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
signs. The current therapeutic regimen for PD is mainly symptomatic as the etio …
[HTML][HTML] Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
The activation of microglia and the various substances they produce have been linked to the
pathologic development of Parkinson's disease (PD), but the precise role of microglia in PD …
pathologic development of Parkinson's disease (PD), but the precise role of microglia in PD …
MPTP-induced parkinsonian model in mice: biochemistry, pharmacology and behavior
N Ogawa, K Mizukawa, Y Hirose, S Kajita… - European …, 1987 - karger.com
The effects of MPTP administered to mice were examined biochemically and
pharmacologically. The dopamine level in the striatum of the mice injected with MPTP …
pharmacologically. The dopamine level in the striatum of the mice injected with MPTP …