Preclinical models of nontuberculous mycobacteria infection for early drug discovery and vaccine research
E Rampacci, V Stefanetti, F Passamonti… - Pathogens, 2020 - mdpi.com
Nontuberculous mycobacteria (NTM) represent an increasingly prevalent etiology of soft
tissue infections in animals and humans. NTM are widely distributed in the environment and …
tissue infections in animals and humans. NTM are widely distributed in the environment and …
The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases
SL Baldwin, SE Larsen, D Ordway… - PLoS neglected …, 2019 - journals.plos.org
Seemingly innocuous nontuberculous mycobacteria (NTM) species, classified by their slow
or rapid growth rates, can cause a wide range of illnesses, from skin ulceration to severe …
or rapid growth rates, can cause a wide range of illnesses, from skin ulceration to severe …
Non-tuberculous mycobacterial disease: progress and advances in the development of novel candidate and repurposed drugs
Y Gu, W Nie, H Huang, X Yu - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens that can infect all body
tissues and organs. In particular, the lungs are the most commonly involved organ, with NTM …
tissues and organs. In particular, the lungs are the most commonly involved organ, with NTM …
In vitro drug discovery models for Mycobacterium tuberculosis relevant for host infection
T Parish - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction: Tuberculosis is the leading cause of death from infectious disease. Current
drug therapy requires a combination of antibiotics taken over> 6 months. An urgent need for …
drug therapy requires a combination of antibiotics taken over> 6 months. An urgent need for …
Drug testing in mouse models of tuberculosis and nontuberculous mycobacterial infections
BV Nikonenko, AS Apt - Tuberculosis, 2013 - Elsevier
Mice as a species are susceptible to tuberculosis infection while mouse inbred strains
present wide spectrum of susceptibility/resistance to this infection. However, non …
present wide spectrum of susceptibility/resistance to this infection. However, non …
An ex vivo culture model for screening drug activity against in vivo phenotypes of Mycobacterium tuberculosis
DJ Turner, SL Hoyle, VA Snewin, MP Gares… - …, 2002 - microbiologyresearch.org
Since the activity of drugs against Mycobacterium tuberculosis grown in microbiological
culture can differ from their activity against bacteria present in infected tissues, compounds …
culture can differ from their activity against bacteria present in infected tissues, compounds …
State-of-the-art treatment strategies for nontuberculous mycobacteria infections
MC Muñoz-Egea, N Carrasco-Antón… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction Non-tuberculous Mycobacteria (NTM) are a group of organisms
whose importance in medicine seems to be increasing in recent times. The increasing …
whose importance in medicine seems to be increasing in recent times. The increasing …
Antimycobacterial strategies to evade antimicrobial resistance in the nontuberculous mycobacteria
The nontuberculous mycobacteria (NTM) have recently emerged as important bacterial
pathogens of both animals and humans. Of particular, concern is the high level of …
pathogens of both animals and humans. Of particular, concern is the high level of …
Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria
J van Ingen, MJ Boeree, D van Soolingen… - Drug Resistance …, 2012 - Elsevier
Nontuberculous mycobacteria (NTM) are increasingly recognized as causative agents of
opportunistic infections in humans. For most NTM infections the therapy of choice is drug …
opportunistic infections in humans. For most NTM infections the therapy of choice is drug …
Discovery of Common Putative Drug Targets and Vaccine Candidates for Mycobacterium tuberculosis sp.
RM Nalamolu, C Pasala, SK Katari… - Journal of Drug Delivery …, 2019 - jddtonline.info
Mycobacterium tuberculosis is the bacteria that cause tuberculosis (TB), an infection that
usually affects the lungs and can be fatal without proper treatment. Combating through …
usually affects the lungs and can be fatal without proper treatment. Combating through …