Method for estimating disease risk from microbiome data using structural equation modeling

H Tokuno, T Itoga, J Kasuga, K Okuma… - Frontiers in …, 2023 - frontiersin.org
The relationship between the human gut microbiota and disease is of increasing scientific
interest. Previous investigations have focused on the differences in intestinal bacterial …

Gut microbiota and atopic dermatitis: a two-sample Mendelian randomization study

Y Xue, L Zhang, Y Chen, H Wang, J Xie - Frontiers in Medicine, 2023 - frontiersin.org
Background Accumulating evidence suggests that alterations in gut microbiota composition
and diversity are associated with Atopic dermatitis (AD). But until now, the causal …

Do we need to change our perspective about gut biomarkers? A public data mining approach to identify differentially abundant bacteria in intestinal inflammatory …

L Vega, L Bohórquez, JD Ramírez… - Frontiers in cellular and …, 2022 - frontiersin.org
Introduction The gut microbiome is involved in multiple processes that influence host
physiology, and therefore, disruptions in microbiome homeostasis have been linked to …

Amadis: a comprehensive database for association between microbiota and disease

L Li, Q Jing, S Yan, X Liu, Y Sun, D Zhu… - Frontiers in …, 2021 - frontiersin.org
The human gastrointestinal tract represents a symbiotic bioreactor that can mediate the
interaction of the human host. The deployment and integration of multi-omics technologies …

Evaluation of gut microbiota predictive potential associated with phenotypic characteristics to identify multifactorial diseases

DC Fonseca, I Marques Gomes da Rocha… - Gut …, 2024 - Taylor & Francis
Gut microbiota has been implicated in various clinical conditions, yet the substantial
heterogeneity in gut microbiota research results necessitates a more sophisticated approach …

Determine independent gut microbiota-diseases association by eliminating the effects of human lifestyle factors

C Zhu, X Wang, J Li, R Jiang, H Chen, T Chen… - BMC microbiology, 2022 - Springer
Lifestyle and physiological variables on human disease risk have been revealed to be
mediated by gut microbiota. Low concordance between case-control studies for detecting …

Deciphering associations between gut microbiota and clinical factors using microbial modules

R Wang, X Zheng, F Song, MH Wong, KS Leung… - …, 2023 - academic.oup.com
Motivation Human gut microbiota plays a vital role in maintaining body health. The dysbiosis
of gut microbiota is associated with a variety of diseases. It is critical to uncover the …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Gut microbiota composition is related to AD pathology

BJH Verhaar, HMA Hendriksen, FA de Leeuw… - Frontiers in …, 2022 - frontiersin.org
Introduction Several studies have reported alterations in gut microbiota composition of
Alzheimer's disease (AD) patients. However, the observed differences are not consistent …

Statistical modeling of gut microbiota for personalized health status monitoring

J Zhu, H Xie, Z Yang, J Chen, J Yin, P Tian, H Wang… - Microbiome, 2023 - Springer
Background The gut microbiome is closely associated with health status, and any microbiota
dysbiosis could considerably impact the host's health. In addition, many active consortium …