Adiponectin, an adipocyte-derived hormone, regulates glucose and lipid metabolism. It is
also antiinflammatory. During obesity, adiponectin levels and sensitivity are reduced …

Peripheral adiponectin acts on the hypothalamus to inhibit energy expenditure and increase
food intake through its receptors AdipoR1 and adipoR2. The hypothalamic expression of …

Adiponectin and its receptors play an important role in energy homeostasis and insulin
resistance, but their regulation remains to be fully elucidated. We hypothesized that high-fat …

Adiponectin is involved in the control of energy homeostasis in peripheral tissues through
Adipor1 and Adipor2 receptors. An increasing amount of evidence suggests that this …

Adiponectin is known to be an anti‐diabetic adipocytokine. However, the action mechanism
by which it produces this effect remains controversial. In the present study, we investigated …

Adiponectin is an abundantly expressed adipokine in adipose tissue and has direct insulin
sensitizing activity. A decrease in the circulating levels of adiponectin by interactions …

Adiponectin exerts an insulin-sensitizing effect, improving insulin action in peripheral tissues
and restraining insulin resistance. Here, we explore the hypothesis that adiponectin can …

Adiponectin is an adipocyte-derived factor that plays a pivotal role in lipid and glucose
metabolism. Recently, two types of adiponectin receptors (AdipoR1 and AdipoR2) were …

Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance.
Obesity in adulthood is characterized by adipocyte hypertrophy. Adipose tissue participates …

The adipocyte-derived hormone adiponectin regulates glucose and lipid metabolism and
influences the risk for developing obesity, type 2 diabetes, and cardiovascular disease …