Comparative safety and effectiveness of direct-acting oral anticoagulants versus warfarin: a national cohort study of nursing home residents

M Alcusky, J Tjia, DD McManus, AL Hume… - Journal of General …, 2020 - Springer
Background Research comparing direct-acting oral anticoagulants (DOACs) to warfarin has
excluded nursing home residents, a vulnerable and high-risk population. Objective To …

Prevalence and the factors associated with oral anticoagulant use among nursing home residents

Q Chen, K Lapane, AP Nunes, J Tjia… - Journal of clinical …, 2021 - Wiley Online Library
Abstract What is Known and Objective Anticoagulants are indicated for treatment and
prevention of several clinical conditions. Prior studies have examined anticoagulant …

Changes in anticoagulant utilization among United States nursing home residents with atrial fibrillation from 2011 to 2016

M Alcusky, DD McManus, AL Hume… - Journal of the …, 2019 - Am Heart Assoc
Background Nursing home residents with atrial fibrillation are at high risk for ischemic stroke
and bleeding events. The most recent national estimate (2004) indicated less than one third …

Benefits and Harms of Standard Versus Reduced‐Dose Direct Oral Anticoagulant Therapy for Older Adults With Multiple Morbidities and Atrial Fibrillation

KN Hayes, T Zhang, DH Kim, LA Daiello… - Journal of the …, 2023 - Am Heart Assoc
Background Dose reduction of direct oral anticoagulant (DOAC) medications is
inconsistently applied to older adults with multiple morbidities, potentially due to perceived …

Dosing accuracy of direct oral anticoagulants in an academic medical center

JB Schwartz, S Merrill, N de Leon… - Journal of hospital …, 2017 - Wiley Online Library
BACKGROUND/OBJECTIVE Direct‐acting oral anticoagulants (DOACs) are increasingly
used to prevent or treat thromboembolism. We conducted a study to compare how well initial …

Comparison of the effectiveness and safety of direct oral anticoagulants: a nationwide propensity score–weighted study

AB Ingason, JP Hreinsson, AS Agustsson… - Blood …, 2023 - ashpublications.org
In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral
anticoagulants (DOACs) had similar or even superior efficacy and safety compared with …

Clinician trends in prescribing direct oral anticoagulants for US Medicare beneficiaries

KM Wheelock, JS Ross, K Murugiah, Z Lin… - JAMA network …, 2021 - jamanetwork.com
Importance Contemporary national clinical practice guidelines recommend direct-acting oral
anticoagulants (DOACs) as the first-line anticoagulant strategy over warfarin for most …

Effectiveness and safety of direct oral anticoagulants compared to warfarin in treatment naïve non-valvular atrial fibrillation patients in the US Department of defense …

K Gupta, J Trocio, A Keshishian, Q Zhang… - BMC cardiovascular …, 2019 - Springer
Background Clinical trials have demonstrated that direct oral anticoagulants (DOACs) are at
least non-inferior to warfarin in reducing the risk of stroke/systemic embolism (SE) among …

Dose specific effectiveness and safety of DOACs in patients with non-valvular atrial fibrillation: A Canadian retrospective cohort study

E Rahme, R Godin, H Nedjar, K Dasgupta… - Thrombosis …, 2021 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) have been proven to be effective
and safe for prevention of ischemic stroke and systemic embolism in patients with non …

Real-world direct comparison of the effectiveness and safety of apixaban, dabigatran, rivaroxaban, and warfarin in Medicare beneficiaries with atrial fibrillation

L Yang, MM Brooks, NW Glynn, Y Zhang… - The American journal of …, 2020 - Elsevier
It remains unknown whether the comparative effectiveness of direct oral anticoagulants
(DOACs) and warfarin differs between atrial fibrillation patients with and without a history of …