Cell-derived extracellular vesicles for CRISPR/Cas9 delivery: engineering strategies for cargo packaging and loading
Y Liang, Z Iqbal, J Wang, L Xu, X Xu, K Ouyang… - Biomaterials …, 2022 - pubs.rsc.org
Genome editing technology has emerged as a potential therapeutic tool for treating
incurable diseases. In particular, the discovery of clustered regularly interspaced short …
incurable diseases. In particular, the discovery of clustered regularly interspaced short …
Current and prospective strategies for advancing the targeted delivery of CRISPR/Cas system via extracellular vesicles
X Huang, A Li, P Xu, Y Yu, S Li, L Hu… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) have emerged as a promising platform for gene delivery owing
to their natural properties and phenomenal functions, being able to circumvent the …
to their natural properties and phenomenal functions, being able to circumvent the …
Nanovesicle-mediated delivery systems for CRISPR/Cas genome editing
Genome-editing technology has emerged as a potential tool for treating incurable diseases
for which few therapeutic modalities are available. In particular, discovery of the clustered …
for which few therapeutic modalities are available. In particular, discovery of the clustered …
Exosomes as targeted delivery platform of CRISPR/Cas9 for therapeutic genome editing
L Duan, K Ouyang, J Wang, L Xu, X Xu, C Wen… - …, 2021 - Wiley Online Library
Therapeutic genome editing harnesses the power of genome editing tools to correct
erroneous genes associated with disease pathology. To bring the CRISPR/Cas9 tool from …
erroneous genes associated with disease pathology. To bring the CRISPR/Cas9 tool from …
[HTML][HTML] Nanocarriers: A novel strategy for the delivery of CRISPR/Cas systems
In recent decades, clustered regularly interspaced short palindromic repeat/CRISPR
associated protein (CRISPR/Cas) has become one of the most promising genome editing …
associated protein (CRISPR/Cas) has become one of the most promising genome editing …
Tropism-facilitated delivery of CRISPR/Cas9 system with chimeric antigen receptor-extracellular vesicles against B-cell malignancies
Q Xu, Z Zhang, L Zhao, Y Qin, H Cai, Z Geng… - Journal of controlled …, 2020 - Elsevier
The CRISPR/Cas9 system is an efficient genome-editing system that has been successfully
applied in the field of gene therapy. However, clinical applications of the CRISPR/Cas9 …
applied in the field of gene therapy. However, clinical applications of the CRISPR/Cas9 …
Recent advances in CRISPR/Cas9 delivery strategies
BH Yip - Biomolecules, 2020 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has
revolutionized the field of gene editing. Continuous efforts in developing this technology …
revolutionized the field of gene editing. Continuous efforts in developing this technology …
Gene editing by extracellular vesicles
CRISPR/Cas technologies have advanced dramatically in recent years. Many different
systems with new properties have been characterized and a plethora of hybrid CRISPR/Cas …
systems with new properties have been characterized and a plethora of hybrid CRISPR/Cas …
Challenges in CRISPR/CAS9 delivery: potential roles of nonviral vectors
CRISPR/Cas9 genome editing platforms are widely applied as powerful tools in basic
research and potential therapeutics for genome regulation. The appropriate alternative of …
research and potential therapeutics for genome regulation. The appropriate alternative of …
Biomaterial-assisted targeted and controlled delivery of CRISPR/Cas9 for precise gene editing
RISPR-Cas9 has exhibited enormous potential in gene therapy. It can perform genome
editing with single-nucleotide precision in various types of cell and tissue, providing a …
editing with single-nucleotide precision in various types of cell and tissue, providing a …