Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid “ …
DA Mandour, MA Bendary, AE Alsemeh - Journal of Molecular Histology, 2021 - Springer
Alzheimer's disease (AD) is a chronic age-related neurodegenerative disease characterized
by degeneration of the central cholinergic neurons, inflammation and oxidative stress in the …
by degeneration of the central cholinergic neurons, inflammation and oxidative stress in the …
Hesperidin ameliorates cognitive dysfunction, oxidative stress and apoptosis against aluminium chloride induced rat model of Alzheimer's disease
A Justin Thenmozhi, TR William Raja… - Nutritional …, 2017 - Taylor & Francis
Background/aims: Deregulation of metal ion homeostasis has been assumed as one of the
key factors in the progression of neurodegenerative diseases. Aluminium (Al) has been …
key factors in the progression of neurodegenerative diseases. Aluminium (Al) has been …
Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment …
Recent attention is given to the influence of dietary supplementation on health and mental
well-being. Oxidative stress is associated with many diseases including neurodegenerative …
well-being. Oxidative stress is associated with many diseases including neurodegenerative …
[HTML][HTML] Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer's …
AH Moghaddam, M Zare - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Alzheimer disease (AD) is a progressive dementia affecting a large proportion of the aging
population. There is evidence that brain tissue in patients with AD is exposed to oxidative …
population. There is evidence that brain tissue in patients with AD is exposed to oxidative …
Hesperidin, a citrus flavonoid, has the ameliorative effects against experimental autoimmune encephalomyelitis (EAE) in a C57BL/J6 mouse model
The aim of this study was determined the effects of Hesperidin (HP) on neuronal damage in
brain tissue caused by Experimental allergic encephalomyelitis (EAE), an established model …
brain tissue caused by Experimental allergic encephalomyelitis (EAE), an established model …
Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic …
IO Ishola, AA Jacinta, OO Adeyemi - Metabolic Brain Disease, 2019 - Springer
Alzheimer disease (AD) is an age related neurodegenerative disease causing severe
cognitive and memory decline in elderly people. Flavonoids play neuroprotective role by …
cognitive and memory decline in elderly people. Flavonoids play neuroprotective role by …
Neuroprotective effects of chronic hesperetin administration in mice
EJ Choi, WS Ahn - Archives of pharmacal research, 2008 - Springer
Flavonoids are considered therapeutic agents in neurodegenerative disease because of
their neuroprotective activity. This study investigated the neuroprotective effects of …
their neuroprotective activity. This study investigated the neuroprotective effects of …
Hesperetin confers neuroprotection by regulating Nrf2/TLR4/NF-κB signaling in an Aβ mouse model
Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. No
comprehensive studies have shown its protective effects in neurodegenerative disorders …
comprehensive studies have shown its protective effects in neurodegenerative disorders …
Effects of delphinidin on pathophysiological signs of nucleus basalis of Meynert lesioned rats as animal model of Alzheimer disease
S Heysieattalab, L Sadeghi - Neurochemical Research, 2020 - Springer
Alzheimer's disease (AD) is an advanced neurodegenerative disorder greatly accompanied
by cognitive deficits, oxidative stress, inflammation, amyloid plaques deposition, and …
by cognitive deficits, oxidative stress, inflammation, amyloid plaques deposition, and …
Standardized Hypericum perforatum reduces oxidative stress and increases gene expression of antioxidant enzymes on rotenone-exposed rats
MI Sánchez-Reus, MAG Del Rio, I Iglesias, M Elorza… - …, 2007 - Elsevier
Since oxidative stress is implicated in the pathophysiology of dementia and depression, this
study was designed to investigate the pro-oxidant activity of rotenone, the protective role of …
study was designed to investigate the pro-oxidant activity of rotenone, the protective role of …