Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps …

MA Pacheco, KA Schneider, Q Cheng, EO Munde… - Malaria Journal, 2020 - Springer
Background Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation
approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in …

Prevalence of pfdhfr and pfdhps mutations in Plasmodium falciparum associated with drug resistance among pregnant women receiving IPTp-SP at Msambweni …

SW Gikunju, EL Agola, RO Ondondo, J Kinyua… - Malaria journal, 2020 - Springer
Background Prevention and treatment of malaria during pregnancy is crucial in dealing with
maternal mortality and adverse fetal outcomes. The World Health Organization …

Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012

DW Juma, AA Omondi, L Ingasia, B Opot, A Cheruiyot… - Malaria journal, 2014 - Springer
Abstract Background Sulphadoxine-pyrimethamine (SP), an antifolate, was replaced by
artemether-lumefantrine as the first-line malaria drug treatment in Kenya in 2004 due to the …

Prevalence of molecular markers of resistance to sulfadoxine–pyrimethamine before and after community delivery of intermittent preventive treatment of malaria in …

A Figueroa-Romero, D Bissombolo… - The Lancet global …, 2023 - thelancet.com
Background The effectiveness of community delivery of intermittent preventive treatment (C-
IPT) of malaria in pregnancy (IPTp) with sulfadoxine–pyrimethamine has been evaluated in …

High Prevalence of Molecular Markers of Plasmodium falciparum Resistance to Sulphadoxine–Pyrimethamine in Parts of Ghana: A Threat to ITPTp-SP?

LL Afutu, JN Boampong… - Journal of Tropical …, 2021 - academic.oup.com
Malaria in pregnancy is a huge public health problem as it is the cause of maternal anaemia,
still birth, premature delivery, low birth weight among others. To tackle this problem, WHO …

Prevalence of the Pfdhfr and Pfdhps mutations among asymptomatic pregnant women in Southeast Nigeria

E Esu, C Tacoli, P Gai, N Berens-Riha, M Pritsch… - Parasitology …, 2018 - Springer
Sulfadoxine-pyrimethamine (SP) is the recommended drug for intermittent preventive
treatment of malaria in pregnancy in most of sub-Saharan Africa. Resistance to SP is related …

[HTML][HTML] Surveillance of molecular markers of Plasmodium falciparum resistance to sulphadoxine-pyrimethamine 5 years after the change of malaria treatment policy …

NO Duah, NB Quashie, BK Abuaku… - The American journal …, 2012 - ncbi.nlm.nih.gov
Abstract In 2005, sulphadoxine-pyrimethamine (SP) became the drug of choice for
intermittent preventive treatment of Plasmodium falciparum malaria in pregnancy (IPTp) in …

High prevalence of dhfr and dhps molecular markers in Plasmodium falciparum in pregnant women of Nchelenge district, Northern Zambia

MNP Siame, S Mharakurwa, J Chipeta, P Thuma… - Malaria journal, 2015 - Springer
Background Sulphadoxine-pyrimethamine (SP) is the recommended drug for intermittent
preventive treatment in pregnancy (IPTp) in most African countries, including Zambia …

Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Central Africa between 2016 and 2021: wide geographic …

X Wang, X Zhang, H Chen, Q Lu, W Ruan… - Microbiology …, 2022 - Am Soc Microbiol
Sulfadoxine-pyrimethamine (SP) resistance impairs the efficacy of antimalarial drugs.
Monitoring molecular markers in exported malaria infections provides an efficient way to …

High levels of sulphadoxine-pyrimethamine resistance Pfdhfr-Pfdhps quintuple mutations: a cross sectional survey of six regions in Tanzania

SI Matondo, GS Temba, AA Kavishe, JS Kauki… - Malaria Journal, 2014 - Springer
Background In 2006, the first-line anti-malarial drug treatment in Tanzania was changed
from sulphadoxine-pyrimethamine (SP) to artemether-lumefantrine (ALu), an artemisinin …