Efficacy of SARS-CoV-2 vaccines and the dose–response relationship with three major antibodies: a systematic review and meta-analysis of randomised controlled …

ZR Yang, YW Jiang, FX Li, D Liu, TF Lin… - The Lancet …, 2023 - thelancet.com
Background The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness
and death is uncertain due to the rarity of data in individual trials. How well the antibody …

Efficacy and effectiveness of SARS-CoV-2 vaccines: a systematic review and meta-analysis

RM Ghazy, R Ashmawy, NA Hamdy, YAM Elhadi… - Vaccines, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has threatened global health and
prompted the need for mass vaccination. We aimed to assess the efficacy and effectiveness …

A Meta-Analysis on the Safety and Immunogenicity of CovId-19 vaccines

R Ashmawy, NA Hamdy, YAM Elhadi… - Journal of Primary …, 2022 - journals.sagepub.com
Objective: The presented meta-analysis (MA) aims at identifying the vaccine safety and
immunogenicity in published trials about SARS-CoV-2 vaccines. Methods: All relevant …

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

ARYB Lee, SY Wong, LYA Chai, SC Lee, MX Lee… - Bmj, 2022 - bmj.com
Objective To compare the efficacy of covid-19 vaccines between immunocompromised and
immunocompetent people. Design Systematic review and meta-analysis. Data sources …

[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2

SH Hodgson, K Mansatta, G Mallett, V Harris… - The lancet infectious …, 2021 - thelancet.com
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …

Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis

D Cromer, M Steain, A Reynaldi, TE Schlub… - Nature …, 2023 - nature.com
Vaccine protection from symptomatic SARS-CoV-2 infection has been shown to be strongly
correlated with neutralising antibody titres; however, this has not yet been demonstrated for …

Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1–2 …

PA Goepfert, B Fu, AL Chabanon… - The Lancet Infectious …, 2021 - thelancet.com
Summary Background CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine
produced in a baculovirus expression system being developed against SARS-CoV-2. We …

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled …

Y Zhang, G Zeng, H Pan, C Li, Y Hu, K Chu… - The Lancet infectious …, 2021 - thelancet.com
Background With the unprecedented morbidity and mortality associated with the COVID-19
pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac …

SARS-CoV-2 neutralizing antibodies: a network meta-analysis across vaccines

P Rogliani, A Chetta, M Cazzola, L Calzetta - Vaccines, 2021 - mdpi.com
Background: There are no studies providing head-to-head comparison across SARS-CoV-2
vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing …

Duration of effectiveness of vaccines against SARS-CoV-2 infection and COVID-19 disease: results of a systematic review and meta-regression

DR Feikin, MM Higdon, LJ Abu-Raddad, N Andrews… - The lancet, 2022 - thelancet.com
Background Knowing whether COVID-19 vaccine effectiveness wanes is crucial for
informing vaccine policy, such as the need for and timing of booster doses. We aimed to …