Diagnostics and Therapeutic Potential of miR-205 and miR-34a in Ovarian Cancer Management: A miRNA-Target-Based Analysis

V Kumar, A Pandey, A Arora, P Gautam… - DNA and Cell …, 2023 - liebertpub.com
Epithelial ovarian cancer (EOC) treatment strategies mainly focused on surgery combined
with chemotherapy. Recent targeted therapy techniques emerge as milestone and could be …

[HTML][HTML] miRNA-200a/c as potential biomarker in epithelial ovarian cancer (EOC): evidence based on miRNA meta-signature and clinical investigations

Y Teng, X Su, X Zhang, Y Zhang, C Li, W Niu, C Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Extensive effort has been put on miRNA expression signatures in epithelial ovarian cancer
(EOC). Unfortunately, consistent conclusion rarely yielded from diverse studies, mainly due …

[HTML][HTML] Candidate microRNA biomarkers in human epithelial ovarian cancer: systematic review profiling studies and experimental validation

Y Chen, L Zhang, Q Hao - Cancer cell international, 2013 - Springer
Despite advances in detection and therapy, epithelial ovarian cancer (EOC) still represents
the most lethal gynecologic malignancy in women worldwide. The high mortality of EOC is …

[HTML][HTML] High-throughput sequencing identification of differentially expressed microRNAs in metastatic ovarian cancer with experimental validations

Y Gu, S Zhang - Cancer Cell International, 2020 - Springer
Background Ovarian cancer (OC) is a common gynecological cancer and characterized by
high metastatic potential. MicroRNAs (miRNAs, miRs) have the promise to be harnessed as …

[HTML][HTML] MicroRNA-based signatures impacting clinical course and biology of ovarian cancer: a miRNOmics study

E Krasniqi, A Sacconi, D Marinelli, L Pizzuti… - Biomarker …, 2021 - Springer
Abstract Background In Western countries, ovarian cancer (OC) still represents the leading
cause of gynecological cancer-related deaths, despite the remarkable gains in therapeutical …

[HTML][HTML] Evaluation of diagnostic potential of epigenetically deregulated MiRNAs in epithelial ovarian cancer

V Kumar, S Gupta, A Chaurasia, M Sachan - Frontiers in Oncology, 2021 - frontiersin.org
Background Epithelial ovarian cancer (EOC) is one of the most lethal gynecological
malignancies among women worldwide. Early diagnosis of EOC could help in ovarian …

[HTML][HTML] MicroRNA Gene Expression Signature Driven by miR-9 Overexpression in Ovarian Clear Cell Carcinoma

N Yanaihara, Y Noguchi, M Saito, M Takenaka… - PloS one, 2016 - journals.plos.org
Previous studies have identified microRNA (miRNA) involvement in human cancers. This
study aimed to elucidate potential clinical and biological associations of ovarian cancer …

1073 High-throughput epigenomic analysis point to MIR-145–3P as a potential therapeutic target in advanced high-grade serous ovarian cancer

E González-Cantó, S Tomás-Pérez, BA Mc Cormack… - 2024 - ijgc.bmj.com
Introduction/Background High-grade serous ovarian cancer (HGSOC) is the most lethal
gynecologic cancer for which no curative treatment exists. miRNAs are small non-coding …

[HTML][HTML] MicroRNA‑655 inhibits cell proliferation and invasion in epithelial ovarian cancer by directly targeting vascular endothelial growth factor Retraction in/10.3892 …

Z Zhao, S Yang, Y Cheng… - Molecular medicine …, 2018 - spandidos-publications.com
In recent years, microRNAs (miRNAs/miRs) have been shown to be deregulated in epithelial
ovarian cancer (EOC). Their deregulation has been suggested to be involved in EOC …

MicroRNA as biomarker in ovarian cancer management: Advantages and challenges

V Kumar, S Gupta, K Varma, M Sachan - DNA and Cell Biology, 2020 - liebertpub.com
Ovarian cancer is the most prevalent gynecological malignancy affecting women throughout
the globe. Ovarian cancer has several subtypes, including epithelial ovarian cancer (EOC) …