Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature
spermatozoa are transcriptionally and translationally inactive and incapable of protein …

BACKGROUND The human sperm cell is very well suited for proteomic studies, as it is
accessible, can be easily purified and is believed to be transcriptionally and translationally …

Among its many functions, the ubiquitin–proteasome system regulates substrate-specific
proteolysis during the cell cycle, apoptosis, and fertilization and in pathologies such as …

Proteins in the seminal fluid of animals with internal fertilization effect numerous responses
in mated females that impact both male and female fertility. Among these proteins is the …

The 26 S proteasome is responsible for regulated proteolysis in eukaryotic cells. It is
composed of one 20 S core particle (CP) flanked by one or two 19 S regulatory particles …

Background Male-factor infertility presents a vexing problem for many reproductively active
couples. Many studies have focused on abnormal sperm parameters. Recent advances in …

It has been proposed that a chymotrypsin-like enzyme plays a key role in sperm penetration
through the vitelline coat of eggs of the ascidian, Halocynthia roretzi. In this report, two kinds …

Fertilin is a sperm surface protein with an essential role in fertilization. It is required for the
migration of spermatozoa through the oviduct, for binding to the zona pellucida, and for …

Abstract Ubiquitin is a 8.5-kDa peptide that tags other proteins for proteasomal degradation.
It has been proposed that ubiquitination might be responsible for the elimination of defective …

BACKGROUND: Ubiquitin, a house‐keeping protein that marks other proteins for
proteasomal degradation, tags defective sperm during epididymal passage. To establish …