The glycosphingolipid GD2 as an effective but enigmatic target of passive immunotherapy in children with aggressive neuroblastoma (HR-NBL)
U Rovigatti - Cancer Letters, 2021 - Elsevier
Neuroblastoma (NBL), the most frequent and lethal pediatric cancer of children in pre-school
age, is considered enigmatic in view of its extreme heterogeneity, from spontaneous …
age, is considered enigmatic in view of its extreme heterogeneity, from spontaneous …
Anti-GD2 directed immunotherapy for high-risk and metastatic neuroblastoma
GCF Chan, CM Chan - Biomolecules, 2022 - mdpi.com
Neuroblastoma is one of the few childhood cancers that carries a tumor-specific antigen in
the form of a glycolipid antigen known as GD2. It has restricted expression in normal tissue …
the form of a glycolipid antigen known as GD2. It has restricted expression in normal tissue …
Advances in anti-GD2 immunotherapy for treatment of high-risk neuroblastoma
J Voeller, PM Sondel - Journal of pediatric hematology/oncology, 2019 - journals.lww.com
Neuroblastoma (NBL) is the most common extracranial solid tumor in pediatrics, yet overall
survival is poor for high-risk cases. Immunotherapy regimens using a tumor-selective …
survival is poor for high-risk cases. Immunotherapy regimens using a tumor-selective …
Immunotherapy of Neuroblastoma Targeting GD2 and Beyond
JT Hung, AL Yu - Glycosignals in Cancer: Molecular Assembly and …, 2023 - Springer
Neuroblastoma is the most common extracranial solid tumor in children. Although low-risk
neuroblastoma is mostly curable, the outcome of high-risk neuroblastoma, which …
neuroblastoma is mostly curable, the outcome of high-risk neuroblastoma, which …
Neuroblastoma origin and therapeutic targets for immunotherapy
IV Kholodenko, DV Kalinovsky… - Journal of …, 2018 - Wiley Online Library
Neuroblastoma is a pediatric solid cancer of heterogeneous clinical behavior. The unique
features of this type of cancer frequently hamper the process of determining clinical …
features of this type of cancer frequently hamper the process of determining clinical …
Anti-GD2 immunotherapy for neuroblastoma
S Sait, S Modak - Expert review of anticancer therapy, 2017 - Taylor & Francis
Introduction: Current therapeutic approaches for high-risk neuroblastoma (HR-NB) include
high-dose chemotherapy, surgery and radiotherapy; interventions that are associated with …
high-dose chemotherapy, surgery and radiotherapy; interventions that are associated with …
GD2‐targeted immunotherapy and potential value of circulating microRNAs in neuroblastoma
S Gholamin, H Mirzaei, SM Razavi… - Journal of cellular …, 2018 - Wiley Online Library
Neuroblastoma (NB) with various clinical presentation is a known childhood malignancy.
Despite significant progress in treatment of NB afflicted patients, high risk disease is usually …
Despite significant progress in treatment of NB afflicted patients, high risk disease is usually …
Immunotherapy of neuroblastoma: facts and hopes
While the adoption of multimodal therapy including surgery, radiation, and aggressive
combination chemotherapy has improved outcomes for many children with high-risk …
combination chemotherapy has improved outcomes for many children with high-risk …
Gd2 expression in Medulloblastoma and neuroblastoma for personalized Immunotherapy: A matter of subtype
C Paret, A Ustjanzew, S Ersali, L Seidmann… - Cancers, 2022 - mdpi.com
Simple Summary Molecular analyses discussed in Molecular Tumor Boards are expected to
improve cancer treatment by identifying tumor-specific alterations. Here, we quantified the …
improve cancer treatment by identifying tumor-specific alterations. Here, we quantified the …
The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells
A Kowalczyk, M Gil, I Horwacik, Ż Odrowąż, D Kozbor… - Cancer letters, 2009 - Elsevier
Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. The majority
of children suffers from high risk neuroblastoma and has disseminated disease at the time of …
of children suffers from high risk neuroblastoma and has disseminated disease at the time of …