Cardiac baroreflex dysfunction in patients with pulmonary arterial hypertension at rest and during orthostatic stress: role of the peripheral chemoreflex

M Paula-Ribeiro, IC Ribeiro… - Journal of Applied …, 2021 - journals.physiology.org
The baroreflex integrity in early-stage pulmonary arterial hypertension (PAH) remains
uninvestigated. A potential baroreflex impairment could be functionally relevant and possibly …

[HTML][HTML] Testing individual baroreflex responses to hypoxia-induced peripheral chemoreflex stimulation

H Kronsbein, DA Gerlach, K Heusser, A Hoff… - Clinical Autonomic …, 2020 - Springer
Introduction Baroreflexes and peripheral chemoreflexes control efferent autonomic activity
making these reflexes treatment targets for arterial hypertension. The literature on their …

Carotid chemoreflex activity restrains post‐exercise cardiac autonomic control in healthy humans and in patients with pulmonary arterial hypertension

M Paula‐Ribeiro, IC Ribeiro, LC Aranda… - The Journal of …, 2019 - Wiley Online Library
Key points Dysfunction of post‐exercise cardiac autonomic control is associated with
increased mortality risk in healthy adults and in patients with cardiorespiratory diseases. The …

[HTML][HTML] Arterial baroreflex sensitivity: Relationship with peripheral chemoreflex in patients with chronic heart failure

N Trembach, I Zabolotskikh - Artery Research, 2018 - Elsevier
Background The purpose of this study was to evaluate the relationship between the breath-
holding duration and the sensitivity of the arterial baroreflex, as well as the prognostic value …

Ventilatory baroreflex sensitivity in humans is not modulated by chemoreflex activation

JM Stewart, E Rivera, DA Clarke… - American Journal …, 2011 - journals.physiology.org
Increasing arterial blood pressure (AP) decreases ventilation, whereas decreasing AP
increases ventilation in experimental animals. To determine whether a “ventilatory …

Peripheral chemoreflex and baroreflex interactions in cardiovascular regulation in humans

JR Halliwill, BJ Morgan… - The Journal of …, 2003 - Wiley Online Library
We tested the hypothesis that activation of peripheral chemoreceptors with acute isocapnic
hypoxia resets arterial baroreflex control of both heart rate and sympathetic vasoconstrictor …

Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in essential hypertension

CN Joseph, C Porta, G Casucci, N Casiraghi… - …, 2005 - Am Heart Assoc
Sympathetic hyperactivity and parasympathetic withdrawal may cause and sustain
hypertension. This autonomic imbalance is in turn related to a reduced or reset arterial …

Sympathetic baroreceptor regulation during hypoxic hypotension in humans: new insights

C Janssen, G Grassi, D Laude… - Journal of …, 2018 - journals.lww.com
Background: Baroreceptor activation by a continuous infusion of phenylephrine selectively
abolishes the muscle sympathetic nerve activity (MSNA) response to hypoxia in humans …

Peripheral chemoreflex activation contributes to sympathetic baroreflex impairment in chronic heart failure

F Despas, E Lambert, A Vaccaro… - Journal of …, 2012 - journals.lww.com
Background: Chemoreflex-mediated sympathetic activation contributes to both initiation and
progression of chronic heart failure (CHF). Method: To study the direct role of increased …

Within-breath sympathetic baroreflex sensitivity is modulated by lung volume but unaffected by acute intermittent hypercapnic hypoxia in men

M Nardone, AL Teixeira, AV Incognito… - American Journal …, 2020 - journals.physiology.org
Muscle sympathetic nerve activity (MSNA) exhibits well-described within-breath respiratory
modulation, but the interactive contributions of the arterial baroreflex remain unclear. The …