[PDF][PDF] Brain virtual histology with X-ray phase-contrast tomography

M Chourrout, H Rositi, E Ong, V Hubert… - Part I: whole-brain … - academia.edu
White-matter injury leads to severe functional loss in many neurological diseases. Myelin
staining on histological samples is the most common technique to investigate white-matter …

[PDF][PDF] Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

B Lyon - 2022 - researchgate.net
White-matter injury leads to severe functional loss in many neurological diseases. Myelin
staining on histological samples is the most common technique to investigate white-matter …

Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

M Chourrout, H Rositi, E Ong, V Hubert… - Biomedical optics …, 2022 - opg.optica.org
White-matter injury leads to severe functional loss in many neurological diseases. Myelin
staining on histological samples is the most common technique to investigate white-matter …

Brain virtual histology with X-ray phase-contrast tomography Part II: 3D morphologies of amyloid-β plaques in Alzheimer's disease models

M Chourrout, M Roux, C Boisvert, C Gislard… - Biomedical optics …, 2022 - opg.optica.org
While numerous transgenic mouse strains have been produced to model the formation of
amyloid-β (Aβ) plaques in the brain, efficient methods for whole-brain 3D analysis of Aβ …

X-ray phase contrast tomography serves preclinical investigation of neurodegenerative diseases

F Palermo, N Pieroni, L Maugeri… - Frontiers in …, 2020 - frontiersin.org
We report a qualitative study on central nervous system (CNS) damage that demonstrates
the ability of X-ray phase contrast tomography (XPCT) to confirm data obtained with …

[HTML][HTML] Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer's disease

M Töpperwien, F van der Meer, C Stadelmann, T Salditt - NeuroImage, 2020 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder which is characterized by
increasing dementia. It is accompanied by the development of extracellular β-amyloid …

Virtual histopathology of Alzheimer's disease

M Chourrout - 2023 - univ-lyon1.hal.science
Alzheimer's disease is the most frequent dementia among the elderly, as it affects more than
30 million people worldwide. Its pathological pathway involves the aggregation of two …

Assessment of plaque morphology in Alzheimer's mouse cerebellum using three-dimensional X-ray phase-based virtual histology

L Massimi, N Pieroni, L Maugeri, M Fratini, F Brun… - Scientific reports, 2020 - nature.com
Visualization and characterization of β-amyloid deposits is a fundamental task in pre-clinical
study of Alzheimer's disease (AD) to assess its evolution and monitor the efficiency of new …

3D imaging of protein aggregates in human neurodegeneration by multiscale X-ray phase-contrast tomography

J Reichmann, J Franz, M Eckermann, C Stadelmann… - 2024 - europepmc.org
This study leverages X-ray phase-contrast tomography (XPCT) for detailed analysis of
neurodegenerative diseases like Alzheimer's and Parkinson's, focusing on the 3D …

[图书][B] 3d virtual histology of neuronal tissue by propagation-based x-ray phase-contrast tomography

M Töpperwien - 2018 - books.google.com
Deciphering the three-dimensional (3d) cytoarchitecture of neuronal tissue is an important
step towards understanding the connection between tissue function and structure and …