Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles

ST Larsen, P Jackson, SS Poulsen, M Levin… - …, 2016 - Taylor & Francis
Metal oxide nanoparticles are used in a broad range of industrial processes and workers
may be exposed to aerosols of the particles both during production and handling. Despite …

A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro

ACA Dankers, CF Kuper, AJ Boumeester… - Journal of Applied …, 2018 - Wiley Online Library
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled
metal oxide NPs may generate inflammation. The aim of this study was to investigate the …

[HTML][HTML] Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

JD Sisler, R Li, W McKinney, RR Mercer, Z Ji… - Particle and fibre …, 2015 - Springer
Background Although classified as metal oxides, cobalt monoxide (CoO) and lanthanum
oxide (La 2 O 3) nanoparticles, as representative transition and rare earth oxides, exhibit …

[HTML][HTML] Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials

R Landsiedel, L Ma-Hock, T Hofmann… - Particle and fibre …, 2014 - Springer
Background A standard short-term inhalation study (STIS) was applied for hazard
assessment of 13 metal oxide nanomaterials and micron-scale zinc oxide. Methods Rats …

Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing

WS Cho, R Duffin, CA Poland… - Environmental …, 2010 - ehp.niehs.nih.gov
Background Metal oxide nanoparticles (NPs) have been widely used in industry, cosmetics,
and biomedicine. Objectives We examined hazards of several well-characterized high …

Toxicity assessment of metal oxide nanomaterials using in vitro screening and murine acute inhalation studies

S Areecheewakul, A Adamcakova-Dodd, BE Givens… - NanoImpact, 2020 - Elsevier
Characterizations and in vitro toxicity screening were performed on metal oxide engineered
nanomaterials (ENMs) independently comprising ZnO, CuO, CeO 2, Fe 2 O 3, WO 3, V 2 O …

Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells

B Fahmy, SA Cormier - Toxicology in Vitro, 2009 - Elsevier
Metal oxide nanoparticles are often used as industrial catalysts and elevated levels of these
particles have been clearly demonstrated at sites surrounding factories. To date, limited …

Short-term inhalation of cadmium oxide nanoparticles alters pulmonary dynamics associated with lung injury, inflammation, and repair in a mouse model

JL Blum, LK Rosenblum, G Grunig… - Inhalation …, 2014 - Taylor & Francis
Abstract Context: Cadmium oxide nanoparticles (CdO NPs) are employed in optoelectronic
devices and as a starting material for generating quantum dots as well as for medical …

[HTML][HTML] Toxicokinetics of nanoparticles deposited in lungs using occupational exposure scenarios

O Creutzenberg, G Pohlmann, D Schaudien… - Frontiers in Public …, 2022 - frontiersin.org
Various synthetic powders with primary particle sizes at the nanoscale and a high
commercial impact have been studied using Wistar rats. The test materials were metal …

Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure

I Gosens, FR Cassee, M Zanella, L Manodori… - …, 2016 - Taylor & Francis
Introduction: Increased use of nanomaterials has raised concerns about the potential for
undesirable human health and environmental effects. Releases into the air may occur and …