Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work,
we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates …

Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-
described virulence determinants. A polysaccharide capsule and the ability to produce …

Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

The production of melanin pigments is associated with virulence for many microbes. Melanin
is believed to contribute to microbial virulence by protecting microbial cells from oxidative …

Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Cryptococcus-macrophage interaction is crucial in the development of cryptococcocal
diseases. C. neoformans and C. gattii are major pathogenic species that occupy different …

Cryptococcus neoformans strains exhibit considerable phenotype variability with regards to
the capsular polysaccharide, sterol composition of the cell wall, and cell and colony …

Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

The ability of fungi to transition between unicellular and multicellular growth has a profound
impact on our health and the economy. Many important fungal pathogens of humans …

Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize …