Hepatitis B virus (HBV) infection is a major global health problem with no established cure.
Dedicator of cytokinesis 11 (DOCK11), known as a guanine nucleotide exchange factor …

HBV infection is challenging to cure due to the persistence of viral covalently closed circular
viral DNA (cccDNA). The dedicator of cytokinesis 11 (DOCK11) is recognized as a guanine …

Background & Aims Hepatitis B virus (HBV) infection is difficult to cure owing to the
persistence of covalently closed circular viral DNA (cccDNA). We performed single-cell …

Abstract Background Hepatitis B Virus (HBV) is the most common cause of chronic liver
disease worldwide. The mechanisms that regulate HBV viral replication remain poorly …

Human hepatitis B virus (HBV) infection remains a serious health problem worldwide.
However, the mechanism for the maintenance of HBV in a latent state within host cells …

Current therapies for hepatitis B virus (HBV) cannot completely eliminate the HBV genome
because of the stable population of covalently closed circular DNA (cccDNA) and so on. FIT …

Background. We recently established a monoclonal antibody (2-152a MAb) that binds to 3β-
hydroxysterol-Δ24-reductase (DHCR24) by immunizing mice with cells (RzM6-LC) …

Infection with hepatitis B virus (HBV) cannot be cured completely because of the persistence
of covalently closed circular DNA (cccDNA). We previously found that the host gene …

Abstract Dedicator of cytokinesis 2 (DOCK2) is a key molecule for lymphocyte activation and
migration. DOCK2 interacts with Ras-related C3 botulinus toxin substrate 1 (Rac1, GTPase) …

The covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is a viral center
molecule for HBV infection and persistence. However, the cellular restriction factors of HBV …