Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo

Z Song, R Feng, M Sun, C Guo, Y Gao, L Li… - Journal of colloid and …, 2011 - Elsevier
The aim of this study was to assess the potential of new copolymeric micelles to modify the
pharmacokenetics and tissue distribution of Curcumin (CUR), a hydrophobic drug. In the …

Galactosamine-modified PEG-PLA/TPGS micelles for the oral delivery of curcumin

S Sun, X Du, M Fu, AR Khan, J Ji, W Liu… - International Journal of …, 2021 - Elsevier
In this study, galactosamine-modified poly (ethylene glycol)-poly (lactide)(Gal-PEG-PLA)
polymers were synthesized and Gal-PEG-PLA/D-α-tocopherol polyethylene glycol 1000 …

[HTML][HTML] Biodegradable m-PEG/PCL core-shell micelles: preparation and characterization as a sustained release formulation for curcumin

H Danafar, S Davaran, K Rostamizadeh… - Advanced …, 2014 - ncbi.nlm.nih.gov
Purpose: Among the potent anticancer agents, curcumin is known as a very efficacious
against many different types of cancer cells, but its clinical applications has been limited …

Pharmacokinetics and in vivo delivery of curcumin by copolymeric mPEG-PCL micelles

HK Manjili, P Ghasemi, H Malvandi, MS Mousavi… - European Journal of …, 2017 - Elsevier
Curcumin (CUR) has been associated with anti-inflammatory, antimicrobial, antioxidant, anti-
amyloid, and antitumor effects, but its application is limited because of its low aqueous …

Evaluation in vitro and in vivo of curcumin-loaded mPEG-PLA/TPGS mixed micelles for oral administration

Y Duan, B Zhang, L Chu, HHY Tong, W Liu… - Colloids and Surfaces B …, 2016 - Elsevier
The aim of this work is to prepare and characterize curcumin-loaded methoxy poly (ethylene
glycol)-poly (lactide)(mPEG-PLA)/D-α-tocopherol polyethylene glycol 1000 succinate …

Polymeric micelles for parenteral delivery of curcumin: preparation, characterization and in vitro evaluation

L Song, Y Shen, J Hou, L Lei, S Guo, C Qian - Colloids and Surfaces A …, 2011 - Elsevier
Amphiphilic methoxypoly (ethylene glycol)-b-poly (ɛ-caprolactone-co-p-dioxanone)[MPEG-
P (CL-co-PDO)] copolymers were synthesized and characterized by 1H NMR and gel …

Linolenic acid-modified PEG-PCL micelles for curcumin delivery

Z Song, W Zhu, N Liu, F Yang, R Feng - International journal of …, 2014 - Elsevier
In this study, a novel linolenic acid-modified poly (ethylene glycol)-b-poly (ϵ-caprolactone)
copolymer was prepared through radical addition, ring-opening polymerization, and N …

Curcumin-encapsulated MePEG/PCL diblock copolymeric micelles: a novel controlled delivery vehicle for cancer therapy

C Mohanty, S Acharya, AK Mohanty, F Dilnawaz… - …, 2010 - Future Medicine
Aim: To develop a suitable formulation of curcumin-encapsulated methoxy poly (ethylene
glycol)(MePEG)/poly-ε-caprolactone (PCL) diblock copolymeric micelle by varying the …

Cholesterol-conjugated poly (D, L-lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in cancer therapy

P Kumari, OS Muddineti, SVK Rompicharla… - Drug …, 2017 - Taylor & Francis
Polymeric micelles have been widely explored preclinically as suitable delivery systems for
poorly soluble chemotherapeutic drugs in cancer therapy. The present study reported the …

PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment

X Chen, J Chen, B Li, X Yang, R Zeng, Y Liu… - Journal of colloid and …, 2017 - Elsevier
Abstract Poly (d, l-lactide-co-glycolide)-poly (ethylene glycol)-poly (d, l-lactide-co-glycolide)
triblock copolymers (PLGA-PEG-PLGA) has been proven to be desirable for anti-cancer …