The Road to HTLV-1-Induced Leukemia by Following the Subcellular Localization of HTLV-1-Encoded HBZ Protein

RS Accolla - Frontiers in Immunology, 2022 - frontiersin.org
Human T cell leukemia virus-1 (HTLV-1) is the causative agent of a severe cancer of the
lymphoid lineage that develops in 3-5% of infected individuals after many years. HTLV-1 …

Molecular and Cellular Mechanism of Leukemogenesis of ATL: Emergent Evidence of a Significant Role for HBZ in HTLV‐1‐Induced Pathogenesis

Y Satou, M Matsuoka - Leukemia Research and Treatment, 2012 - Wiley Online Library
Adult T‐cell leukemia (ATL) is a leukemia derived from mature CD4+ T cells and induced by
human T‐cell leukemia virus type 1 (HTLV‐1) infection. Previous studies have revealed …

HTLV-1 replication and adult T cell leukemia development

CZ Giam - Viruses and Human Cancer: From Basic Science to …, 2021 - Springer
Human T-cell leukemia virus type 1 (HTLV-1) is a complex human delta retrovirus that
infects an estimated 10–20 million people worldwide (Gessain and Cassar 2012). HTLV-1 …

A preclinical model for the atll lymphoma subtype with insights into the role of microenvironment in HTLV-1-mediated lymphomagenesis

M Vicario, A Mattiolo, B Montini, MA Piano… - Frontiers in …, 2018 - frontiersin.org
Adult T cell Leukemia/Lymphoma (ATLL) is a mature T cell malignancy associated with
Human T cell Leukemia Virus type 1 (HTLV-1) infection. Among its four main clinical …

The state of the art in the pathogenesis of ATL and new potential targets associated with HTLV-1 and ATL

K Murata, Y Yamada - International Reviews of Immunology, 2007 - Taylor & Francis
Almost 30 years have passed since adult T-cell leukemia (ATL) was identified as a new
disease entity in Japan. During this period, its causative agent, human T-cell leukemia virus …

Human T-cell lymphotropic virus type 1 and its oncogenesis

L Zhang, J Wei, L Wang, S Huang… - Acta Pharmacologica …, 2017 - nature.com
Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiologic agent of adult T-cell
leukemia/lymphoma (ATL), a rapidly progressing clonal malignancy of CD4+ T lymphocytes …

[HTML][HTML] Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach

MM Forghani-Ramandi, B Mostafavi, A Bahavar… - Virus Research, 2023 - Elsevier
Background Adult T-cell leukemia/lymphoma (ATLL) is a poor prognosis malignancy of
peripheral T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The low survival …

[HTML][HTML] What is adult T-cell leukemia pathogenesis? System virology as a solution of this puzzle

M Karbalaei, M Keikha - Jundishapur Journal of Chronic Disease …, 2019 - brieflands.com
Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP) and the adult T-cell leukemia/lymphoma …

[引用][C] Role of HTLV‐1 proviral DNA load and clonality in the development of adult T‐cell leukemia/lymphoma in asymptomatic carriers

A Okayama, S Stuver, M Matsuoka… - … journal of cancer, 2004 - Wiley Online Library
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent for adult T-cell
leukemia/lymphoma (ATL). 1–3 Only a small proportion of HTLV-1 carriers eventually …

Mouse Models for HTLV-1 Infection and Adult T Cell Leukemia

S Nakajima, K Okuma - International Journal of Molecular Sciences, 2023 - mdpi.com
Adult T cell leukemia (ATL) is an aggressive hematologic disease caused by human T cell
leukemia virus type 1 (HTLV-1) infection. Various animal models of HTLV-1 infection/ATL …