Genetic modification of animals via selective breeding is the basis for modern agriculture.
The current breeding paradigm however has limitations, chief among them is the …

Domestic pigs are the second most important source of meat world-wide, and the genetic
improvement of economic traits, such as meat production, growth, and disease resistance, is …

Genetically modified animals, especially rodents, are widely used in biomedical research.
However, non-rodent models are required for efficient translational medicine and preclinical …

Milk and meat from cattle and buffaloes contribute 45% of the global animal protein supply,
followed by chickens (31%), and pigs (20%). In 2016, the global cattle population of 1.0 …

The ability to directly manipulate the pig genome through genetic engineering has been
available to the research community for over three decades. This technology has …

Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …

Germline editing, the process by which the genome of an individual is edited in such a way
that the change is heritable, has been applied to a wide variety of animals [DA Sorrell, AF …

In recent years there has been a veritable explosion in the use of genome editors to create
sitespecific changes, both in vitro and in vivo, to the genomes of a multitude of species for …

Humans have a long history in shaping the genetic makeup of livestock to optimize
production and meet growing human demands for food and other animal products. Until …

• Methods for genome editing have developed over the past decades, making the
technology more efficient and specific.• Technology to generate edited pigs and chickens is …