Elucidating the Immunological Function of the Cryptococcus Neoformans Capsule

A Vecchiarelli, E Pericolini, E Gabrielli… - Future …, 2013 - Taylor & Francis
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans

D Decote-Ricardo, IF LaRocque-de-Freitas… - Frontiers in …, 2019 - frontiersin.org
Cryptococcosis is a systemic fungal infection caused by Cryptococcus neoformans. In
immunocompetent patients, cryptococcal infection is often confined to the lungs. In …

Capsular Material of Cryptococcus neoformans: Virulence and Much More

A Vecchiarelli, C Monari - Mycopathologia, 2012 - Springer
The capsule is generally considered one of the more powerful virulence factors of
microorganisms, driving research in the field of microbial pathogenesis and in the …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

How does Cryptococcus get its coat?

TL Doering - Trends in microbiology, 2000 - cell.com
During the past few decades, increasing attention has focused on pathogenic fungi both as
fascinating research subjects and as the agents of serious illness in diverse patient …

What makes Cryptococcus neoformans a pathogen?

KL Buchanan, JW Murphy - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus
neoformans have been increasing steadily over the past 10 years because of the onset of …

Immunoregulation by capsular components of Cryptococcus neoformans

A Vecchiarelli - Medical mycology, 2000 - academic.oup.com
Cryptococcus neoformans is an encapsulated yeast that is pathogenic for humans. The
capsule is a major virulence factor composed mainly of glucuronoxylomannan (GXM) and …

The environmental yeast Cryptococcus liquefaciens produces capsular and secreted polysaccharides with similar pathogenic properties to those of C. neoformans

GRS Araújo, GJC Freitas, FL Fonseca, PEC Leite… - Scientific reports, 2017 - nature.com
Invasive fungal infections, including cryptococcosis, are a growing threat to
immunocompromised patients. Although Cryptococcus neoformans and Cryptococcus gattii …

The Capsule of Cryptococcus neoformans Reduces T-Lymphocyte Proliferation by Reducing Phagocytosis, Which Can Be Restored with Anticapsular Antibody

RM Syme, TF Bruno, TR Kozel, CH Mody - Infection and immunity, 1999 - Am Soc Microbiol
Cell-mediated immunity is critical for the host defense to Cryptococcus neoformans, as
demonstrated by numerous animal studies and the prevalence of the infection in AIDS …