Microbiota modulation as preventative and therapeutic approach in Alzheimer's disease

L Bonfili, V Cecarini, O Gogoi, C Gong… - The FEBS …, 2021 - Wiley Online Library
The gut microbiota coevolves with its host, and numerous factors like diet, lifestyle, drug
intake and geographical location continuously modify its composition, deeply influencing …

Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

P Kesika, N Suganthy, BS Sivamaruthi, C Chaiyasut - Life sciences, 2021 - Elsevier
Gut microbiota represents a diverse and dynamic population of microorganisms harboring
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

D Goyal, SA Ali, RK Singh - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
Alzheimer's disease (AD) is a complex multifactorial disease involving chronic
neuroinflammation and neurodegeneration. It has been recently recognized that gut …

[HTML][HTML] Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels

L Bonfili, V Cecarini, S Berardi, S Scarpona… - Scientific reports, 2017 - nature.com
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …

[HTML][HTML] Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

R Solanki, A Karande, P Ranganathan - Frontiers in Neurology, 2023 - frontiersin.org
Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder,
characterized by neuroinflammation and extracellular aggregation of Aβ peptide …

[HTML][HTML] Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies

D Seo, DM Holtzman - Experimental & Molecular Medicine, 2024 - nature.com
Alzheimer's disease (AD) is a fatal progressive neurodegenerative disease. Despite
tremendous research efforts to understand this complex disease, the exact pathophysiology …

Role of microbial dysbiosis in the pathogenesis of Alzheimer's disease

G Susmitha, R Kumar - Neuropharmacology, 2023 - Elsevier
Alzheimer's disease (AD) is the leading cause of dementia in the elderly and detected
during the advanced stages where the chances of reversal are minimum. The gut-brain axis …

[HTML][HTML] The immunopathogenesis of Alzheimer's disease is related to the composition of gut microbiota

F Leblhuber, D Ehrlich, K Steiner, S Geisler, D Fuchs… - Nutrients, 2021 - mdpi.com
The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …

[HTML][HTML] Roles and mechanisms of gut microbiota in patients with Alzheimer's disease

S Wu, X Liu, R Jiang, X Yan, Z Ling - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common age-related progressive neurodegenerative
disease, characterized by a decline in cognitive function and neuronal loss, and is caused …

[HTML][HTML] The microbiota–gut–brain axis and Alzheimer's disease: neuroinflammation is to blame?

A Megur, D Baltriukienė, V Bukelskienė, A Burokas - Nutrients, 2020 - mdpi.com
For years, it has been reported that Alzheimer's disease (AD) is the most common cause of
dementia. Various external and internal factors may contribute to the early onset of AD. This …