The gut-brain axis, including the microbiome, leaky gut and bacterial translocation: mechanisms and pathophysiological role in Alzheimer's disease

CA Kohler, M Maes, A Slyepchenko… - Current …, 2016 - ingentaconnect.com
Alzheimer's disease (AD), the most common form of dementia, is a progressive disorder
manifested by gradual memory loss and subsequent impairment in mental and behavioral …

Unveiling the role of gut-brain axis in regulating neurodegenerative diseases: A comprehensive review

H Yadav, R Bhardwaj, A Bakshi, S Gupta, SK Maurya - Life Sciences, 2023 - Elsevier
Emerging evidence have shown the importance of gut microbiota in regulating brain
functions. The diverse molecular mechanisms involved in cross-talk between gut and brain …

Alzheimer's disease and gastrointestinal microbiota; impact of Helicobacter pylori infection involvement

M Doulberis, G Kotronis, D Gialamprinou… - International Journal …, 2021 - Taylor & Francis
Background: Alzheimer disease (AD) is a leading cause of global burden with great impact
on societies. Although research is working intensively on promising therapy, the problem …

Human gut microbiota in health and Alzheimer's disease

L Szablewski - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Gut microbiota plays a crucial role in human health and disease. The alterations in the
composition of gut microbiota may cause the onset of certain human pathologies. One of …

Gut microbiota, cognitive frailty and dementia in older individuals: a systematic review

A Ticinesi, C Tana, A Nouvenne, B Prati… - … interventions in aging, 2018 - Taylor & Francis
Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and
physical frailty phenotype in older persons, is increasingly considered the main geriatric …

Gut microbiota regulation and their implication in the development of neurodegenerative disease

P Sun, L Su, H Zhu, X Li, Y Guo, X Du, L Zhang, C Qin - Microorganisms, 2021 - mdpi.com
In recent years, human gut microbiota have become one of the most promising areas of
microorganism research; meanwhile, the inter-relation between the gut microbiota and …

The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline

AS Alsegiani, ZA Shah - Neural Regeneration Research, 2022 - journals.lww.com
Recent emerging research on intestinal microbiota and its contribution to the central nervous
system during health and disease has attracted significant attention. Age-related intestinal …

Gut microbiota and Alzheimer's disease: how to study and apply their relationship

NM Nguyen, J Cho, C Lee - International journal of molecular sciences, 2023 - mdpi.com
Gut microbiota (GM), the microorganisms in the gastrointestinal tract, contribute to the
regulation of brain homeostasis through bidirectional communication between the gut and …

Gut microbiota disorder, gut epithelial and blood–brain barrier dysfunctions in etiopathogenesis of dementia: molecular mechanisms and signaling pathways

MO Welcome - NeuroMolecular Medicine, 2019 - Springer
Emerging evidences indicate a critical role of the gut microbiota in etiopathogenesis of
dementia, a debilitating multifactorial disorder characterized by progressive deterioration of …

Dysbiosis is one of the risk factor for stroke and cognitive impairment and potential target for treatment

M Koszewicz, J Jaroch, A Brzecka, M Ejma… - Pharmacological …, 2021 - Elsevier
More than 50 million people have various forms of cognitive impairment basically caused by
neurodegenerative diseases, such as Alzheimer's, Parkinson's, and cerebrovascular …