[HTML][HTML] Effect of polymeric stabilizers on the size and stability of PLGA paclitaxel nanoparticles
The aim of this study is to formulate polymeric paclitaxel nanoparticles with various
stabilizers to improve solubility, enhance stability, maximize therapeutic efficacy and …
stabilizers to improve solubility, enhance stability, maximize therapeutic efficacy and …
[HTML][HTML] Investigation of effective parameters on size of paclitaxel loaded PLGA nanoparticles
Purpose: The size of polymeric nanoparticles is considered as an effective factor in cancer
therapy due to enterance into tumor tissue via the EPR effect. The purpose of this work was …
therapy due to enterance into tumor tissue via the EPR effect. The purpose of this work was …
Formulation and evaluation of paclitaxel loaded PSA-PEG nanoparticles
R Sharma, M Yasir, S Bhaskar, M Asif - Journal of Applied …, 2011 - japsonline.com
The main objective of this study was to prepare and evaluate PSA-PEG nanoparticles
containing paclitaxel as a model drug by nanoprecipitation method. The influence of …
containing paclitaxel as a model drug by nanoprecipitation method. The influence of …
PLGA 50:50 nanoparticles of paclitaxel: Development, in vitro anti-tumor activity in BT-549 cells and in vivo evaluation
RK Averineni, GV Shavi, AK Gurram… - Bulletin of Materials …, 2012 - Springer
Clinical administration of paclitaxel is hindered due to its poor solubility, which necessitates
the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To …
the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To …
Formulation and in vitro evaluation of paclitaxel loaded nanoparticles
G Aygül, F Yerlikaya, S Caban, İ Vural… - … University Journal of the …, 2013 - dergipark.org.tr
In this study, paclitaxel loaded PLGA nanoparticles were prepared using emulsification-
solvent diffusion method and the influences of polymer and emulsifier concentrations on …
solvent diffusion method and the influences of polymer and emulsifier concentrations on …
Development and evaluation of paclitaxel loaded PLGA: poloxamer blend nanoparticles for cancer chemotherapy
PN Gupta, S Jain, C Nehate, N Alam, V Khare… - International journal of …, 2014 - Elsevier
This investigation described the development of novel PLGA: poloxamer blend
nanoparticles for intravenous administration of paclitaxel in order to limit the cremophor …
nanoparticles for intravenous administration of paclitaxel in order to limit the cremophor …
Nanoparticles of biodegradable polymers for clinical administration of paclitaxel
Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …
which has been found effective against a wide spectrum of cancers including ovarian …
[HTML][HTML] Design and characterization of paclitaxel-loaded polymeric nanoparticles decorated with trastuzumab for the effective treatment of breast cancer
The aim of the study was to design and formulate an antibody-mediated targeted,
biodegradable polymeric drug delivery system releasing drug in a controlled manner to …
biodegradable polymeric drug delivery system releasing drug in a controlled manner to …
Development of stabilized Paclitaxel nanocrystals: In-vitro and in-vivo efficacy studies
Objective The aim of the study was to develop stable Paclitaxel nanocrystals (PTX/NCs) for
enhanced oral delivery of Paclitaxel (PTX) by circumventing its difficult solubilization …
enhanced oral delivery of Paclitaxel (PTX) by circumventing its difficult solubilization …
Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel
Abstract Objective: Paclitaxel (PTX)-loaded polymer (Poly (lactic-co-glycolic acid), PLGA)-
based nanoformulation was developed with the objective of formulating cremophor EL-free …
based nanoformulation was developed with the objective of formulating cremophor EL-free …