[HTML][HTML] Effect of polymeric stabilizers on the size and stability of PLGA paclitaxel nanoparticles

M Sakhi, A Khan, I Khan, SA Khan, SI Khan… - Saudi Pharmaceutical …, 2023 - Elsevier
The aim of this study is to formulate polymeric paclitaxel nanoparticles with various
stabilizers to improve solubility, enhance stability, maximize therapeutic efficacy and …

[HTML][HTML] Investigation of effective parameters on size of paclitaxel loaded PLGA nanoparticles

F Madani, SS Esnaashari, B Mujokoro… - Advanced …, 2018 - ncbi.nlm.nih.gov
Purpose: The size of polymeric nanoparticles is considered as an effective factor in cancer
therapy due to enterance into tumor tissue via the EPR effect. The purpose of this work was …

Formulation and evaluation of paclitaxel loaded PSA-PEG nanoparticles

R Sharma, M Yasir, S Bhaskar, M Asif - Journal of Applied …, 2011 - japsonline.com
The main objective of this study was to prepare and evaluate PSA-PEG nanoparticles
containing paclitaxel as a model drug by nanoprecipitation method. The influence of …

PLGA 50:50 nanoparticles of paclitaxel: Development, in vitro anti-tumor activity in BT-549 cells and in vivo evaluation

RK Averineni, GV Shavi, AK Gurram… - Bulletin of Materials …, 2012 - Springer
Clinical administration of paclitaxel is hindered due to its poor solubility, which necessitates
the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To …

Formulation and in vitro evaluation of paclitaxel loaded nanoparticles

G Aygül, F Yerlikaya, S Caban, İ Vural… - … University Journal of the …, 2013 - dergipark.org.tr
In this study, paclitaxel loaded PLGA nanoparticles were prepared using emulsification-
solvent diffusion method and the influences of polymer and emulsifier concentrations on …

Development and evaluation of paclitaxel loaded PLGA: poloxamer blend nanoparticles for cancer chemotherapy

PN Gupta, S Jain, C Nehate, N Alam, V Khare… - International journal of …, 2014 - Elsevier
This investigation described the development of novel PLGA: poloxamer blend
nanoparticles for intravenous administration of paclitaxel in order to limit the cremophor …

Nanoparticles of biodegradable polymers for clinical administration of paclitaxel

SS Feng, L Mu, KY Win, G Huang - Current Medicinal Chemistry, 2004 - ingentaconnect.com
Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …

[HTML][HTML] Design and characterization of paclitaxel-loaded polymeric nanoparticles decorated with trastuzumab for the effective treatment of breast cancer

M Sakhi, A Khan, Z Iqbal, I Khan, A Raza… - Frontiers in …, 2022 - frontiersin.org
The aim of the study was to design and formulate an antibody-mediated targeted,
biodegradable polymeric drug delivery system releasing drug in a controlled manner to …

Development of stabilized Paclitaxel nanocrystals: In-vitro and in-vivo efficacy studies

S Sharma, A Verma, BV Teja, P Shukla… - European Journal of …, 2015 - Elsevier
Objective The aim of the study was to develop stable Paclitaxel nanocrystals (PTX/NCs) for
enhanced oral delivery of Paclitaxel (PTX) by circumventing its difficult solubilization …

Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel

P Mittal, H Vardhan, G Ajmal, GV Bonde… - Drug development …, 2019 - Taylor & Francis
Abstract Objective: Paclitaxel (PTX)-loaded polymer (Poly (lactic-co-glycolic acid), PLGA)-
based nanoformulation was developed with the objective of formulating cremophor EL-free …