Stroke is defined as a neurological deficit which lasts more than 24 h or leads to death,
which is caused by a focal acute injury to the central nervous system with a vascular origin …

Studies in non-stroke patients have shown an association between dysregulation of the
hypothalamic–pituitary–adrenal axis and morbidity and mortality. We conducted a …

Introduction: Cortisol effects on the brain are exerted through two distinct receptors, inducing
complex and even opposite effects on the cerebral structures implicated in the various …

IntroductionCortisol exerts effects on the brain via two different receptors, producing complex
and sometimes opposite effects on the brain structures involved with the different cognitive …

Progress in treating ischemic stroke (IS) and its delayed consequences has been
frustratingly slow due to the insufficient knowledge on the mechanism. One important factor …

Objective: Elevated cortisol levels have been frequently reported in Alzheimer's disease
(AD) and linked to brain atrophy, especially of the hippocampus. Besides, high cortisol …

Methods: Data from 182 cognitively intact ischemic stroke patients from the TABASCO study
were available. Saliva cortisol levels (bedtime and post-awakening) and cognitive …

Stress is a universal experience for living organisms. Under many circumstances activation
of the hypothalamic–pituitary adrenal (HPA) axis is an adaptive response to stress …

Dementia is an increasing global issue, currently affecting an estimated 50 million people
worldwide. This number is predicted to increase to 82 million by the year 2030, due to the …

Alzheimer's disease (AD) patients show high cortisol levels suggesting that biological
mediators of stress may play a role in the neurodegenerative process of cognitive disorders …