[HTML][HTML] Modeling extracellular matrix-cell interactions in lung repair and chronic disease
TL Hackett, ET Osei - Cells, 2021 - mdpi.com
The lung extracellular matrix (ECM) is a complex and dynamic mixture of fibrous proteins
(collagen, elastin), glycoproteins (fibronectin, laminin), glycosaminoglycans (heparin …
(collagen, elastin), glycoproteins (fibronectin, laminin), glycosaminoglycans (heparin …
Extracellular matrix in lung development, homeostasis and disease
The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
Extracellular matrix as a driver of Chronic Lung diseases
JK Burgess, DJ Weiss… - American Journal of …, 2024 - atsjournals.org
The extracellular matrix (ECM) is not just a three-dimensional scaffold that provides stable
support for all cells in the lungs, but also an important component of chronic fibrotic airway …
support for all cells in the lungs, but also an important component of chronic fibrotic airway …
Matrix remodeling in chronic lung diseases
BH Gu, MC Madison, D Corry, F Kheradmand - Matrix Biology, 2018 - Elsevier
Multicellular organisms synthesize and renew components of their subcellular and
scaffolding proteins, collectively known as the extracellular matrix molecules (ECMs). In the …
scaffolding proteins, collectively known as the extracellular matrix molecules (ECMs). In the …
[HTML][HTML] Chronic lung diseases: entangled in extracellular matrix
JK Burgess, MC Harmsen - European Respiratory Review, 2022 - Eur Respiratory Soc
The extracellular matrix (ECM) is the scaffold that provides structure and support to all
organs, including the lung; however, it is also much more than this. The ECM provides …
organs, including the lung; however, it is also much more than this. The ECM provides …
[HTML][HTML] Extracellular matrix dynamics: tracking in biological systems and their implications
The extracellular matrix (ECM) constitutes the main acellular microenvironment of cells in
almost all tissues and organs. The ECM not only provides mechanical support, but also …
almost all tissues and organs. The ECM not only provides mechanical support, but also …
[HTML][HTML] Extracellular matrix component remodeling in respiratory diseases: what has been found in clinical and experimental studies?
Changes in extracellular matrix (ECM) components in the lungs are associated with the
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease …
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease …
Lung extracellular matrix and fibroblast function
ES White - Annals of the American Thoracic Society, 2015 - atsjournals.org
Extracellular matrix (ECM) is a tissue-specific macromolecular structure that provides
physical support to tissues and is essential for normal organ function. In the lung, ECM plays …
physical support to tissues and is essential for normal organ function. In the lung, ECM plays …
The multi-faceted extracellular matrix: Unlocking its secrets for understanding the perpetuation of lung fibrosis
M Nizamoglu, JK Burgess - Current Tissue Microenvironment Reports, 2021 - Springer
Abstract Purpose of Review Lung fibrosis is currently thought to stem from an aberrant
wound healing response after recurring (micro) injuries in the lung epithelium, together with …
wound healing response after recurring (micro) injuries in the lung epithelium, together with …
[HTML][HTML] Extracellular matrix as a driver of progressive fibrosis
J Herrera, CA Henke… - The Journal of clinical …, 2018 - Am Soc Clin Investig
The extracellular matrix (ECM) is dynamically tuned to optimize physiological function. Its
major properties, including composition and mechanics, profoundly influence cell biology …
major properties, including composition and mechanics, profoundly influence cell biology …