Clustered regularly interspaced palindromic repeats (CRISPR) is a gene editing tool with
tremendous therapeutic potential. Recently, ribonucleoprotein (RNP) complex‐based …

Transient delivery of CRISPR‐based genome editing effectors is important to reduce off‐
target effects and immune responses. Recently extracellular vesicles (EVs) have been …

CRISPR/Cas technologies have advanced dramatically in recent years. Many different
systems with new properties have been characterized and a plethora of hybrid CRISPR/Cas …

The CRISPR gene editing tool holds great potential for curing genetic disorders. However,
the safe, efficient, and specific delivery of the CRISPR/Cas9 components into cells and …

Therapeutic genome editing has the potential to cure diseases by directly correcting genetic
mutations in tissues and cells. Recent progress in the clustered regularly interspaced short …

CRISPR-Cas9 gene editing has emerged as a powerful therapeutic technology, but the lack
of safe and efficient in vivo delivery systems, especially for tissue-specific vectors, limits its …

The method of delivery of CRISPR-Cas9 into target cells is a strong determinant of efficacy
and specificity in genome editing. Even though high efficiency of Cas9 delivery is necessary …

Extracellular vesicles (EVs) have emerged as a promising platform for gene delivery owing
to their natural properties and phenomenal functions, being able to circumvent the …

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has
revolutionized the field of gene editing. Continuous efforts in developing this technology …

Cancers are defined by genetic defects, which underlines the prospect of using gene
therapy in patient care. During the past decade, CRISPR technology has rapidly evolved …