Primary ovarian insufficiency (POI) is an uncommon yet devastating occurrence that results
from a premature depletion of the ovarian pool of primordial follicles. Our understanding of …

Primary ovarian insufficiency (POI) affects∼ 1% of women before 40 years of age. The
recent leap in genetic knowledge obtained by next generation sequencing (NGS) together …

Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …

Primary ovarian insufficiency (POI), also known as premature ovarian failure, is a form of
hypergonadotropic hypogonadism that causes infertility in~ 1% of women< 40 years of age …

In women, the non-growing population of follicles that comprise the ovarian reserve is
determined at birth and serves as the reservoir for future fertility. This reserve of dormant …

Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical
and psychological consequences. Unfortunately, there are many deficiencies in our …

BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …

Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

Ovarian deficiency, including premature ovarian insufficiency (POI) and diminished ovarian
reserve (DOR), represents one of the main causes of female infertility. POI is a genetically …

Primary ovarian insufficiency (POI) occurs in about 1% of female population under the age of
40, leading to reproductive problems, an earlier encounter with menopausal symptoms, and …