Experimental studies have provided strong evidence that chronic inflammation triggered by
the sub-endothelial accumulation of cholesterol-rich lipoproteins in arteries is essential in …

Regulatory T cells (Tregs) play an important role in the regulation of T-cell–mediated
immune responses through suppression of T-cell proliferation and secretion of inhibitory …

Atherosclerosis is an autoimmune disease caused by self-and non-self-antigens
contributing to excessive activation of T and B cell immune responses. These responses …

ABSTRACT T regulatory cells (Tregs) comprise the cardinal mechanism of peripheral
immune tolerance by modulating the function of virtually each immune cell. Given that …

Simple Summary Atherosclerosis is a vascular disease with an asymptomatic debut and
development over decades. The mechanisms of progression of atherosclerosis are not …

Cardiovascular diseases (CVD) are the leading cause of mortality worldwide.
Atherosclerosis is directly associated with CVD and is characterized by slow progressing …

Atherosclerotic diseases, including ischemic heart disease and stroke, are a main cause of
mortality worldwide. Chronic vascular inflammation via immune dysregulation is critically …

Atherosclerosis is a chronic inflammatory disorder involving innate and adaptive immunity
process. Effector T cell (Teff) responses promote atherosclerotic disease, whereas …

Atherosclerosis is a chronic inflammatory disease that is mediated by innate and adaptive
immune responses. The disease is characterized by sub-endothelial accumulation and …

Atherosclerosis involves both innate and adaptive immunity. Here, we provide an overview
of the role of regulatory T (Treg) cells in atherosclerotic diseases. Treg cells and their …