Urolithiasis is closely linked to lifestyle factors. However, the causal relationship and
underlying mechanisms remain unclear. This study aims to investigate the relationship …

Background Urolithiasis is a common urological disease with increasing incidence
worldwide, and preventing its risk poses significant challenges. Here, we used Mendelian …

Background A family history of urolithiasis is associated with a more than doubling of
urolithiasis risk, and a twin study estimating 56% heritability of the condition suggests a …

Objective Few studies have investigated the impact of basal metabolic rate (BMR) on the
development of urolithiasis, and the causal relationship is yet to be established. In this study …

Dietary patterns have a significant impact on the occurrence of urolithiasis. This study aimed
to investigate the causal relationships between the consumption of glucosamine, fresh fruits …

Background The pathogenesis of urolithiasis is multi-factorial and genetic factors have been
shown to play a significant role in the development of urolithiasis. We tried to apply genome …

Objective Previous studies have proposed that food intakes are associated with the risk of
urolithiasis. Here, we conducted a two-sample Mendelian randomization (MR) study to …

Background Earlier studies have warned about the effects of smoking on urolithiasis. Some
studies have deemed that smoking has a promoting effect on urolithiasis, whereas others …

Background: The causal link between smoking, alcohol consumption, and upper urinary
calculi remains uncertain in observational studies due to confounding factors. To uncover …

Background Previous studies have yielded conflicting findings regarding the association
between circulating lipids and lipid-lowering drugs with urinary stones, and the causal …