PLGA-based biodegradable microspheres in drug delivery: recent advances in research and application

Y Su, B Zhang, R Sun, W Liu, Q Zhu, X Zhang… - Drug …, 2021 - Taylor & Francis
Biodegradable microspheres have been widely used in the field of medicine due to their
ability to deliver drug molecules of various properties through multiple pathways and their …

Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects

F Qi, J Wu, H Li, G Ma - Frontiers of Chemical Science and Engineering, 2019 - Springer
Abstract Poly (D, L-lactic-co-glycolic acid)(PLGA)/poly (lactic acid)(PLA) microspheres/
nanoparticles are one of the most successful drug delivery systems (DDS) in lab and clinic …

Poly (lactic-co-glycolic acid) microsphere production based on quality by design: a review

Y Hua, Y Su, H Zhang, N Liu, Z Wang, X Gao, J Gao… - Drug Delivery, 2021 - Taylor & Francis
Poly (lactic-co-glycolic acid)(PLGA) has garnered increasing attention as a candidate drug
delivery polymer owing to its favorable properties, including its excellent biocompatibility …

Synthesis, characterization, biodegradation, and drug delivery application of biodegradable lactic/glycolic acid polymers: Part III. Drug delivery application

XS Wu - Artificial cells, blood substitutes, and biotechnology, 2004 - Taylor & Francis
Lactic/glycolic acid polymers (PLGA) are widely used for drug delivery systems. The
microsphere formulation is the most interesting dosage form of the PLGA-based controlled …

PLGA-based nanoparticles: an overview of biomedical applications

F Danhier, E Ansorena, JM Silva, R Coco… - Journal of controlled …, 2012 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Nano/micro technologies for delivering macromolecular therapeutics using poly (D, L-lactide-co-glycolide) and its derivatives

RC Mundargi, VR Babu, V Rangaswamy… - Journal of Controlled …, 2008 - Elsevier
Biodegradable nano/microparticles of poly (d, l-lactide-co-glycolide)(PLGA) and PLGA-
based polymers are widely explored as carriers for controlled delivery of macromolecular …

Recent advances in the formulation of PLGA microparticles for controlled drug delivery

E Lagreca, V Onesto, C Di Natale, S La Manna… - Progress in …, 2020 - Springer
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

PLGA/PLA-based long-acting injectable depot microspheres in clinical use: production and characterization overview for protein/peptide delivery

A Butreddy, RP Gaddam, N Kommineni… - International journal of …, 2021 - mdpi.com
Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …

Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy

A Narmani, R Jahedi… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction During the last decades, the ever-increasing proportion of patients with cancer
has been led to serious concerns worldwide. Therefore, the development and use of novel …