Omalizumab-Induced Aspirin Tolerance in Nonsteroidal Anti-Inflammatory Drug–Exacerbated Respiratory Disease Patients Is Independent of Atopic Sensitization

T Quint, V Dahm, D Ramazanova, MA Arnoldner… - The Journal of Allergy …, 2022 - Elsevier
Background Nonsteroidal anti-inflammatory drug (NSAID)–exacerbated respiratory disease
(N-ERD) comprises the triad of chronic rhinosinusitis with nasal polyps (CRSwNP), asthma …

Aspirin tolerance in patients with nonsteroidal anti-inflammatory drug–exacerbated respiratory disease following treatment with omalizumab

E Phillips-Angles, P Barranco… - The Journal of …, 2017 - jaci-inpractice.org
Aspirin-exacerbated respiratory disease (AERD) is characterized by the coexistence of
nasal polyps, rhinosinusitis, and asthma, which is exacerbated after the diagnostic or …

[HTML][HTML] Omalizumab ameliorates extrarespiratory symptoms in patients with aspirin-exacerbated respiratory disease

H Hayashi, Y Fukutomi, C Mitsui, K Kajiwara… - Journal of Allergy and …, 2023 - Elsevier
Background Omalizumab, an anti-immunoglobulin E antibody, has clinical efficacy against
respiratory symptoms of aspirin-exacerbated respiratory disease (AERD). However, some …

Omalizumab can inhibit respiratory reaction during aspirin desensitization

DM Lang, MA Aronica, ES Maierson, XF Wang… - Annals of Allergy …, 2018 - Elsevier
Background Aspirin desensitization has been associated with benefit in management of
aspirin-exacerbated respiratory disease (AERD). An intervention that would encourage …

Omalizumab for aspirin hypersensitivity and leukotriene overproduction in aspirin-exacerbated respiratory disease. A randomized controlled trial

H Hayashi, Y Fukutomi, C Mitsui… - American journal of …, 2020 - atsjournals.org
Rationale: Aspirin-exacerbated respiratory disease is characterized by severe asthma,
nonsteroidal antiinflammatory drug hypersensitivity, nasal polyposis, and leukotriene …

Effect of omalizumab on outcomes in patients with aspirin-exacerbated respiratory disease.

T Jean, V Eng, J Sheikh, MS Kaplan… - Allergy & Asthma …, 2019 - search.ebscohost.com
Background: The current treatment for patients with aspirin-exacerbated respiratory disease
(AERD) who have uncontrolled asthma or chronic rhinosinusitis is aspirin desensitization …

[PDF][PDF] Omalizumab in patients with NSAIDs-exacerbated respiratory disease

U Forster-Ruhrmann, D Stergioudi, G Pierchalla… - Rhinology, 2020 - academia.edu
Background: The association of acetylsalicylic acid (ASA) intolerance, chronic rhinosinusitis
with nasal polyps (CRSwNP), asthma, or chronic urticaria is known as NSAID-exacerbated …

Factors reducing omalizumab response in severe asthma

B Sposato, M Scalese, M Milanese, S Masieri… - European journal of …, 2018 - Elsevier
Abstract Background Despite adding Omalizumab to conventional therapy, several severe
asthmatics still show poor disease control. We investigated the factors that may affect a …

Safety and outcomes of aspirin desensitization for aspirin-exacerbated respiratory disease: a single-center study

J Waldram, K Walters, R Simon, K Woessner… - Journal of Allergy and …, 2018 - Elsevier
Background Aspirin desensitization is an effective treatment option for aspirin-exacerbated
respiratory disease. Aspirin desensitization protocol modifications have improved the safety …

[PDF][PDF] Omalizumab decreases exacerbation frequency, oral intake of corticosteroids and peripheral blood eosinophils in atopic patients with uncontrolled asthma

G Pelaia, L Gallelli, P Romeo, T Renda… - International Journal of …, 2011 - core.ac.uk
Omalizumab is a humanized monoclonal anti-IgE antibody approved in 2005 by the
European Medicine Agency (EMA) for the treatment of severe persistent allergic asthma …